Opinion|Videos|September 29, 2025

Economic Burden of Heart Failure Care

Panelists discuss how heart failure creates a massive economic burden of approximately $30 billion annually (expected to reach $70 billion to $80 billion by 2030), driven by hospitalizations, readmissions, expensive multidrug regimens costing over $20,000 to $30,000 per patient, and high-cost interventions like ablations and advanced therapies.

The economic impact of heart failure extends beyond direct medical costs to encompass a complex landscape of expenditures that strain health care systems. Direct costs primarily stem from acute care episodes, hospitalizations, and readmissions, which account for approximately half of the $30 billion annual burden. Pharmacotherapy costs have increased substantially, with comprehensive 5-drug regimens potentially exceeding $20,000 to $30,000 annually per patient, representing a significant portion of total treatment expenses.

Less frequent but high-cost interventions are becoming increasingly prevalent as the population ages and survival improves with better treatments. These include atrial fibrillation ablations, cardiac resynchronization therapy, advanced device therapies, and treatments for conditions like amyloid cardiomyopathy. While individually expensive, these interventions are occurring more frequently and contributing proportionally more to the overall economic burden of heart failure management.

The financial implications extend to value-based care models where organizations assume total cost-of-care responsibility. This creates strong incentives to improve outcomes while controlling expenses, leading to innovative approaches in population health management. The Medicare Shared Savings Program and Accountable Care Organization REACH programs include specific cardiology quality measures with financial ramifications, including preventable heart failure admissions, postdischarge follow-up, β-blocker and angiotensin-converting enzyme inhibitor/angiotensin receptor blocker/angiotensin receptor‐neprilysin inhibitor utilization, and left ventricular function assessment, directly linking clinical performance to economic outcomes.

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