Clinical

The AJMC® clinical page includes all the published content across AJMC.com, The American Journal of Managed Care® and Evidence-Based Oncology™ on a variety of specialties, including dermatology, cardiology, oncology, and rheumatology.

FDA Gives Priority Review to Risdiplam in SMA for Infants Younger Than 2 Months

January 25th 2022, 10:45pm

Article

Risdiplam is approved for children older than 2 months with spinal muscular atrophy (SMA); an expanded approval would include the youngest infants before they show symptoms.

Individualizing Therapy in Patient Subpopulations Without Compromising Contracts

January 25th 2022, 5:01pm

Video

The panel closes the program with giving their final thoughts on individualizing therapies for plaque psoriasis and metabolic syndrome in specific patient subpopulations.

Support Services to Help Patient Adherence

January 25th 2022, 4:51pm

Video

Drs Lebwohl and Groves list support services to help with patient adherence.

MRD Continues to Reliably Predict Disease Progression in CRC

January 24th 2022, 11:00pm

Article

In this poster presented at the 2022 ASCO Gastrointestinal Cancers Symposium, minimal residual disease (MRD) status as detected by postsurgery plasma cell-free DNA continued its strong track record of being a reliable predictor of disease progression in colorectal cancer (CRC).

Study Details Impacts of Mask, Disinfectant Use on Migraine Severity During COVID-19

January 24th 2022, 9:20pm

Article

Researchers in Turkey analyzed the impacts of mask and disinfectant use among patients with confirmed migraine diagnoses.

Dr David R. Stukus on Eosinophilic Esophagitis Guidelines and the Pattern of Disease

January 24th 2022, 8:15pm

Video

David R. Stukus, MD, FACAAI, of Nationwide Children's Hospital and The Ohio State University College of Medicine, and a board member of the American College of Allergy, Asthma & Immunology, discusses guidelines for eosinophilic esophagitis, as well as some disease patterns that may occur.

Genomic Profiling Uncovers Mutations More Enriched in Early-Onset Colorectal Cancer

January 24th 2022, 6:30pm

Article

Findings presented at the 2022 ASCO Gastrointestinal Cancers Symposium showed no significant differences in tissue and plasma genomic profiles of patients with early-onset and late-onset colorectal cancer, but a greater enrichment of the BRCA1 and PTEN mutations were noted in the tissue of those with early-onset disease.

Study: NGS May Be a Superior Method of Detecting SMN1 Gene Copy Number

January 22nd 2022, 5:45pm

Article

Among the 3 methods used across 478 samples included in the study, next-generation sequencing provided the most favorable results.

PAH Risk Assessment Tools Successfully Predict Survival for 5 Years After Diagnosis

January 22nd 2022, 4:04pm

Article

A review of 3 common risk assessment tools for pulmonary arterial hypertension (PAH) found they successfully predict survival for up to 5 years after initial diagnosis.

Large, Retrospective Study Offers Insight Into AGEP Disease Course, Complications

January 22nd 2022, 1:10pm

Article

Among the most notable findings were that acute generalized exanthematous pustulosis is typically triggered by antimicrobial agents and may be associated with complications of the liver or kidney for some patients.