Clinical

Bepirovirsen data show the potential for a functional cure for chronic hepatitis B by lowering HBsAg and boosting immune control.

As president of the BCBSNC Foundation, Colleen Briggs, MBA, reflects on 25 years of progress and outlines where the organization is headed next.

Carolina Barnett-Tapia, MD, PhD, discusses the results of the ADAPT OCULUS trial, which found promising results for treating patients with ocular myasthenia gravis.

These indications cover HIV, type 1 diabetes, chronic hives, genetic-related hearing loss, and lupus.

Ez-PAVE delivers the first direct trial evidence that targeting LDL below 55 mg/dL is superior to below 70 mg/dL in ASCVD patients—providing proof of concept for treat-to-target strategies and a wake-up call about clinical inertia.

Fatima Cody Stanford, MD, MPH, MPA, exposes obesity health disparities, GLP-1 access hurdles, payer policy fixes, and how stigma in care blocks equitable treatment.

Poor housing affordability and quality raised risks of frailty, disability, and death in older adults, yet neighborhood quality showed no independent association.

New data show how systemic inflammation independently raises the risk of CKD progression and cardiovascular events after acute myocardial infarction.

At NAACOS 2026, experts highlighted how real-world AI tools are improving care delivery, outcomes, and efficiency across the health care landscape.

Marc P. Bonaca, MD, MPH, and Josephine Harrington, MD, discuss the clinical value of the uACR test and why it remains underutilized.

Education on colorectal cancer symptoms and screening can help to prevent advancing disease in a cancer that is seeing increased incidence in younger adults.

FIT-DNA modestly improved CRC screening in CHCs, but uptake and follow-up colonoscopy rates remained low.

Patients with advanced glaucoma had better outcomes when treated with trabeculectomy rather than using medication first.

Wastewater SARS-CoV-2 levels correlated with hospital COVID-19 cases, supporting targeted screening of asymptomatic patients.

The BCBSNC Foundation's focus on access to care, health through food, and youth mental health aligns with broader national health trends.

Behavioral text nudges outperformed nurse calls, boosting FIT completion by 9 percentage points at an FQHC while saving staff time.

Beyond standard risk scores, the guideline highlights key risk enhancers—including lipoprotein(a), inflammation markers, and women's health factors—and elevates coronary artery calcium scoring as a Class I tool for resolving uncertainty in primary prevention.

Long-acting CAB+RPV may maintain efficacy even with delayed injections, offering real-world flexibility.

Neoadjuvant immunotherapy is expanding treatment options in CSCC by shrinking complex tumors, improving surgical outcomes, and potentially enhancing long-term disease control.

A 2-week sleep/light intervention shifted teens’ circadian timing earlier, increasing weeknight sleep by about 47 minutes in a randomized trial.

OCM showed no increased likelihood of starting systemic therapy in patients with newly diagnosed cancers, despite gains in poor-prognosis cases.

A case study shows positive outcomes following allogeneic stem cell transplantation in a patient with highly refractory MM and therapy-related MDS/AML.

The weekly anifrolumab autoinjector for systemic lupus erythematosus enables at-home use and improves convenience on top of standard therapy.

A French real-world study of 282 patients with CLL identified 2 distinct treatment profiles shaped by age, genetics, and logistics—not trial data alone.

Phase 3 TETON-1 trial shows inhaled treprostinil improves FVC in IPF, signaling a potential new antifibrotic option.