Clinical

Combination Treatment Maintains Quality of Life in Relapsed/Refractory MM

February 20th 2021, 11:00pm

Article

Health-related quality of life was maintained when treating relapsed/refractory multiple myeloma (RRMM) with daratumumab in combination with bortezomib and dexamethasone.

Progressive MS Alliance Seeks Change to Study Designs to Spur New Therapies

February 20th 2021, 8:45pm

Article

Advocates for patients with progressive multiple sclerosis (MS) want changes in study designs on emerging therapies to speed development and better align with the needs of researchers and patients.

Which Agents Are Linked to Drug- and Toxin-Induced PAH?

February 20th 2021, 5:15pm

Article

In their recently published review, the researchers offer a detailed look at the drugs and toxins associated with drug- and toxin-induced pulmonary arterial hypertension (PAH), as various associations have come to light in recent decades.

Even Patients With Mild CKD Have Higher Hospitalization Rates, Study Says

February 20th 2021, 2:30am

Article

Patients with chronic kidney disease (CKD) healthy enough not to have seen a specialist have higher hospitalization rates than the general population, according to a recent study.

Real-World Study Illustrates Secukinumab’s 24-Month Performance for Psoriatic Arthritis

February 20th 2021, 1:00am

Article

The results from an analysis of patients from 12 rheumatology centers treated with secukinumab for psoriatic arthritis were in line with earlier pivotal trials, the researchers said.

MS Society Releases Guidance on DMT Dosing Modifications for COVID-19 Vaccination

February 19th 2021, 10:08pm

Article

The current guidance emphasizes that the mRNA-based Pfizer/BioNTech and Moderna vaccines are safe for people with multiple sclerosis (MS) taking disease modifying therapies (DMTs).

A Roadmap for Managing Right Ventricular Failure in PH

February 19th 2021, 7:00pm

Article

The researchers prefaced their study by highlighting that pulmonary arterial hypertension (PAH) and all forms of PH continue to be highly morbid and sometimes fatal, particularly in cases requiring hospitalization in the intensive care unit.

Researchers Highlight Clinical Features of AHP, Emergence of siRNA-Based Therapies

February 18th 2021, 5:49pm

Article

A group of researchers discuss the clinical features and diagnosis of acute hepatic porphyrias (AHP) as well as their take on the approval of the first small interfering RNA (siRNA)-based therapy for the treatment of these patients.

Lidocaine Spray Shows Promise for Chronic Cough, Study Says

February 17th 2021, 6:59pm

Article

Lidocaine throat spray can be an effective treatment for refractory chronic cough, according to a recent study.

Spotlight on Clinical Specialties Kicks Off With COPD, SCLC, CAR T

February 17th 2021, 2:23pm

Podcast

On this episode of Managed Care Cast, we highlight a new feature on AJMC.com, the website of The American Journal of Managed Care®, called Clinical Spotlight, where our editors provide a series of interviews with leading experts in certain specialties.