Case Report Describes Bronchiectasis in Patient With NPDB

October 7th 2021, 11:00am


The case suggests lung transplantation can be a feasible option for patients with lung involvement.

Triplet Therapy for PAH May Reduce Disease Progression vs Doublet Therapy

October 6th 2021, 10:45pm


New data on treatment for newly diagnosed pulmonary arterial hypertension (PAH) show initial treatment for the progressive disease that includes macitentan has potential to reduce risk of disease progression.

Liquid Biopsy, Radiological Response Predict Posttreatment Outcomes in BRAF-Mutated Melanoma

October 1st 2021, 11:00pm


In patients with BRAF-mutated melanoma, achieving a complete response and circulating tumor DNA negativity are promising prognostic markers.

Using AI to Predict Outcomes in High-grade Extrauterine Serous Carcinoma

October 1st 2021, 5:00pm


Plasma Lyso-sphingomyelin Levels Predict ASMD Severity, Study Finds

October 1st 2021, 3:30pm


Acid sphingomyelinase deficiency (ASMD) is a rare lysosomal storage disorder; a new report said that plasma lyso-sphingomyelin levels can be used to not only diagnose the rare disease but also predict severity and type.

Comprehensive Genomic Features, Therapeutic Biomarkers Identified in Clear Cell Renal Cell Carcinoma

October 1st 2021, 1:38pm


Investigators reported comprehensive genomic features of patients with clear cell renal cell carcinoma, potentially giving providers a better understanding of the molecular features associated with the disease.

Patient Characteristics Impact Effectiveness of TKIs in CML and AEs Experienced

October 1st 2021, 1:15pm


Dosing from pivotal phase 3 trials of tyrosine kinase inhibitors (TKIs) in chronic myeloid leukemia (CML) is not optimal for real-world patients who experience different efficacy and adverse events (AEs).

FDA Approves Maralixibat to Treat Rare Pediatric Liver Disease

October 1st 2021, 12:45pm


Maralixibat is the first treatment approved for cholestatic pruritus in patients with Alagille syndrome who are 1 year or older.

Neuromuscular Ultrasonography May Have Potential in Assessing SLE

October 1st 2021, 11:00am


A new study suggests the lower-cost, more patient-friendly assessment method may be a useful tool for clinicians.

Dr Ron Eccles on Therapies That Block ATP and Reduce Cough

September 29th 2021, 9:00pm


Therapies that block adenosine triphosphate (ATP) can reduce the irritation that causes cough, and some currently being studied also don’t have taste side effects that can confound clinical trial results, explained Ron Eccles, BSc, PhD, DSc, emeritus profess at Cardiff University.