Researchers Develop AI Model to Predict ICI Response in Advanced Melanoma

November 20th 2020, 5:50pm


Results of the artificial intelligence (AI) model were consistent no matter which immune checkpoint inhibitor (ICI) therapy patients received, suggesting that some biomarkers are not necessarily specific to the checkpoint target.

Risk of Death Differs for Elderly Patients With PAH Taking Endothelin Receptor Antagonists

November 20th 2020, 2:30pm


The mortality risk differs for the 3 endothelin receptor antagonists approved to treat pulmonary arterial hypertension (PAH) in elderly patients; however, a direct comparison in a controlled trial is still needed to confirm results.

Study Identifies Molecular Differences Between Pathogenic, Benign Variants

November 7th 2020, 4:15pm


Understanding these genetic variants discovered through sequencing efforts is key to further progress in clinical genetics.

Balancing Evidence With Action: Dr Patricia Salber Interviews Dr Denise Basow

November 3rd 2020, 10:33pm


With the coronavirus disease 2019 pandemic, new research is quickly being released as more and more is learned. However, the flood of new research needs to be balanced with appropriate review before action is taken.

Use of Triplet Therapy Rose in R/R MM as Deaths Declined, Study Finds

October 29th 2020, 9:45pm


Newer therapies have led to a boost in the number of patients with relapsed or refractory multiple myeloma (R/R MM) who are prescribed triplet regimens. As that shift has occurred, death rates appear to have dropped.

Flawed Racial Assumptions in eGFR Have Care Implications in CKD

October 25th 2020, 6:45pm


The use of estimated glomerular filtration rate (eGFR) equations in assessing chronic kidney disease (CKD) for Black patients may lead to underdiagnosis and undertreatment, according to a nephrologist speaking at Kidney Week.

Over Time, Health Care Costs Move to Forefront for All Patients

October 22nd 2020, 9:12pm


2020 is the 25th anniversary of The American Journal of Managed Care® and the October’s issue of the journal features an interview with Dr Kavita Patel, a nonresident fellow at the Brookings Institution and a primary care physician.

Air Pollution Tied to Higher Hospitalization Risk for PD, Other Neurological Disorders

October 20th 2020, 6:15pm


Air pollution was found to be significantly associated with an increased risk of hospital admissions for several neurological disorders, including Parkinson disease, Alzheimer disease, and other dementias.

AMCP Nexus to Start With Keynote From Surgeon, Transparency Advocate

October 19th 2020, 7:30pm


Attendees at the Academy of Managed Care Pharmacy (AMCP) Nexus 2020 meeting will hear a keynote from a surgeon who has become more visible over the past year and a half discussing what he says are “structural problems” behind the cost of US health care.

Australian Researchers Illustrate Use of ctDNA in Metastatic Breast Cancer

October 17th 2020, 8:00pm


A recent analysis illustrated how a combination of different genomic approaches discovered actionable alterations in 44% of patients with metastatic breast cancer.