Academia

PARP Inhibitors Have Made Significant Progress in BRCA1/2 Metastatic Breast Cancer, but Limitations Remain

April 22nd 2021, 7:56pm

Metastatic breast cancer has a poor prognosis, but emerging targeted therapies are providing some progress in the treatment of the disease, explained Filipa Lynce, MD, medical oncologist at Dana-Farber Cancer Institute and Harvard Medical School.

Some Air Pollutants Linked With Increased Migraine Prevalence, Severity

April 22nd 2021, 12:45pm

Article

Research presented at the American Academy of Neurology's annual meeting indicates some air pollutants may be associated with increased rates of migraine prevalence and severity.

Immunotherapy Combos May Change Prognosis of Late-state or Recurrent EC

April 22nd 2021, 12:41pm

Article

The researchers focused on immunotherapy combinations, which they say may hold promise in the treatment of late-stage or recurrent endometrial cancer (EC).

Better Understanding of Potential Genetic Mutations May Lead to Improved PAH Diagnosis, Treatment

April 13th 2021, 4:25pm

Article

A better understanding of the genetic etiology of pulmonary arterial hypertension and its molecular variants is needed to develop better therapies for the disease, which has no agents available that can reverse or halt it.

“Speckle” Structures Believed to Partner With p53 in Cancer Activity

April 10th 2021, 12:15pm

Article

The study identifies the tumor-suppressing protein p53 as a working partner of “speckles,” nuclear structures that contain proteins and RNA involved in gene expression.

Evaluating Efficacy of Initial Combination Therapy on Pulmonary Vascular Resistance

March 27th 2021, 6:00pm

Article

An ongoing multicenter study in Japan will evaluate reductions in pulmonary vascular resistance 8 months after initiating the combination therapy in pulmonary arterial hypertension.

Looking at Long-term Results, New Opportunities With CAR T-Cell Therapies

March 20th 2021, 6:46pm

Article

Penn Medicine's Stephen Schuster, MD, offers an overview of an eventful year in CAR T-cell therapy at the NCCN Virtual Annual Meeting.

Researchers Identify Patients With COPD at Risk for Hypercapnia Development

March 13th 2021, 4:45pm

Article

Researchers analyzed 2 cohorts of patients with chronic obstructive pulmonary disease (COPD) to characterize who is most at risk for developing hypercapnia and who could most benefit from at-home noninvasive inhalation therapy.

Humana, University of Houston to Offer Program in Value-Based Care Specialization Through Online Program

March 3rd 2021, 2:00pm

Article

The specialization program will teach fundamentals and offer real-world examples of value-based care through an online program.

Diagnosing and Treating Systemic Sclerosis With PAH Remains Challenging

February 27th 2021, 2:30pm

Article

While diagnostic algorithms have evolved in the last decade, there remains an urgent need for innovative therapeutic options to treat systemic sclerosis with pulmonary arterial hypertension.