June 6th 2023
The successful collaboration between a primary care–based network of practices and academic researchers demonstrates feasibility and the need for more funding for primary care research.
Over 6 Years, First-line Brentuximab Vedotin Cuts Risk of Death in Hodgkin Lymphoma by 41%June 4th 2022
Data presented at ASCO show that after 6 years, patients with advanced Hodgkin lymphoma who were treated with a combination of brentuximab vedotin and chemotherapy had a sharply reduced risk of death and a reduced risk of a secondary cancer.
SHINE: Adding Ibrutinib to Treatment Improves PFS by 50% for Older Patients With Mantle Cell LymphomaJune 3rd 2022
Findings from the phase 3 SHINE trial could make ibrutinib the standard treatment option for older patients with mantle cell lymphoma (MCL), who often cannot tolerate chemotherapy or transplant strategies, according to study authors.
Michigan’s Dr Angel Qin Discusses Unmet Need, Clinical Trials in SCLCMay 29th 2022
Angel Qin, MD, clinical assistant professor of medicine at the University of Michigan, discusses the need for more clinical trials in small cell lung cancer and for more patients to qualify for trials.
Emory’s Haumschild on Need for Clinical Pathways in SCLC: “Not Everyone’s an Expert”May 18th 2022
Ryan Haumschild PharmD, MS, MBA, director of Pharmacy Services at Emory Healthcare and Winship Cancer Institute, spoke with AJMC® about health care resource utilization and clinical decision support in the care of patients with small cell lung cancer (SCLC).
Improving Diversity in Clinical Trials: How Early-Stage Investigators Are Reaching Underserved PopulationsApril 13th 2022
Editor’s Note: After this issue of Evidence-Based Oncology™ went to press, Bristol Myers Squibb Foundation announced the $100 million, 5-year initiative will now be called the Robert A. Winn Diversity in Clinical Trials Award Program. The program will also receive a $14 million donation from Gilead Sciences, Inc., over the next 4 years.
Preclinical Data at AACR Show CSP May Be Broad Target in CholangiocarcinomaApril 13th 2022
Researchers presented results for ZB131, a monoclonal antibody that would target cancer-specific plectin (CSP); experiments with mice showed this may be present in more than 80% of the most common types of cholangiocarcinoma.
With Natural Killer Cell Immunotherapy, Alloreactive Cell Dose May Be Predictive of ResponseFebruary 26th 2022
Research has shown that adoptive immunotherapy using natural killer cells may be beneficial in leukemia treatment. The follow-up to a recent study found that the dose of alloreactive natural killer cells matters for treatment response.
Steven Pergam, MD, MPH, Discusses NCCN’s “Strong Preference” for mRNA Vaccines in Patients With Cancer to Prevent COVID-19February 13th 2022
A statement from NCCN’s Advisory Committee on COVID-19 Vaccination and Pre-exposure Prophylaxis said that the panel “endorses vaccination for all eligible persons based on FDA-approved indications or emergency use authorization” and emphasized the need for everyone to be fully vaccinated—including third doses.
CAR T Cells Persist 10 Years After CLL Treatment, Hailed as "Cure"February 3rd 2022
Researchers, as well as a patient who had chronic lymphocytic leukemia (CLL), hailed the findings as a cure, although more work needs to be done to see if the results persist in a larger group of patients.
Stronger Community Connections, Fewer Barriers Are Keys to Better TrialsDecember 19th 2021
Bruce A. Feinberg, DO, of Cardinal Health Specialty Solutions, leads a panel discussion on how far randomized clinical trials have come, how they could be better, and how using real-world evidence could make research more representative of the population.
Using AI to Detect Early Signs of Parkinson Disease Through Facial AnalysisDecember 11th 2021
Researchers at the University of Rochester are analyzing facial muscle movements through videos taken over webcams or smartphones to train a machine learning algorithm with the hope that it can predict Parkinson disease at an earlier stage.
Review Suggests Having IBD May Increase Risk of PDDecember 1st 2021
The meta-analysis sought to clarify previous research, which has explored the idea that Parkinson disease (PD) is tied to inflammation in the gastrointestinal tract, noting that inflammatory bowel disease (IBD) has been implicated in neuroinflammation.
ASOPRS Fall Symposium Will Feature Innovations, Diversity, and Diet PresentationsNovember 9th 2021
The American Society of Ophthalmic Plastic & Reconstructive Surgery 2021 Fall Scientific Symposium will feature presentations on oculofacial surgery innovations, social justice and diversity, and more.
To Prevent the Next Pandemic, Fight Antiscience Beliefs, Hotez SaysNovember 7th 2021
While low- and middle-income countries remain desperate for a COVID-19 vaccine, the United States has entered a dangerous new phase of the pandemic, where antivaccine forces are exporting their antiscience beliefs to other countries, according to a keynote speaker at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting.
Dr Carina Venter on the Gut Microbiome’s Role in Allergic DiseaseNovember 7th 2021
Carina Venter, PhD, RD, allergy specialist dietitian and associate professor in pediatric allergy and immunology at Children's Hospital Colorado and the University of Colorado, discusses the gut microbiome’s complex relationship with our immune system and diet diversity’s potential role in allergic disease and food allergy–related outcomes.
Patients With CTEPH Have Worse Baseline HRQOL Than Patients With IPAHNovember 6th 2021
At baseline, patients with chronic thromboembolic pulmonary hypertension (CTEPH) had worse health-related quality of life (HRQOL) than patients with idiopathic pulmonary arterial hypertension (IPAH), but over time the scores were similar.