Older Adults Are Often Excluded From RCTs of Systemic Treatments for Atopic Dermatitis

December 17th 2020, 2:00pm


Older adults are often at greater risk for adverse events from treatments, but they can also be excluded from randomized controlled trials (RCTs), making it difficult to know if findings are generalizable to this population.

Advice for the Biden Administration About the Challenges in Health Care

December 8th 2020, 11:00pm


This episode of Managed Care Cast is a preview of an interview with Michael E. Chernew, PhD, and A. Mark Fendrick, MD, the co-editors-in-chief of The American Journal of Managed Care®, which appears in the December issue of the journal.

Prostate Cancer Cohort Shows Where Active Surveillance Presents Lowest Risk

December 5th 2020, 11:15pm


Researchers from the University of California San Francisco published their results in the Journal of Urology.

Secukinumab Has a Greater Persistence Rate Than Ustekinumab in Psoriatic Arthritis

December 5th 2020, 5:15pm


In the real world, the persistence rate with secukinumab to treat psoriatic arthritis was higher than with ustekinumab.

Researchers Develop AI Model to Predict ICI Response in Advanced Melanoma

November 20th 2020, 5:50pm


Results of the artificial intelligence (AI) model were consistent no matter which immune checkpoint inhibitor (ICI) therapy patients received, suggesting that some biomarkers are not necessarily specific to the checkpoint target.

Risk of Death Differs for Elderly Patients With PAH Taking Endothelin Receptor Antagonists

November 20th 2020, 2:30pm


The mortality risk differs for the 3 endothelin receptor antagonists approved to treat pulmonary arterial hypertension (PAH) in elderly patients; however, a direct comparison in a controlled trial is still needed to confirm results.

Study Identifies Molecular Differences Between Pathogenic, Benign Variants

November 7th 2020, 4:15pm


Understanding these genetic variants discovered through sequencing efforts is key to further progress in clinical genetics.

Balancing Evidence With Action: Dr Patricia Salber Interviews Dr Denise Basow

November 3rd 2020, 10:33pm


With the coronavirus disease 2019 pandemic, new research is quickly being released as more and more is learned. However, the flood of new research needs to be balanced with appropriate review before action is taken.

Use of Triplet Therapy Rose in R/R MM as Deaths Declined, Study Finds

October 29th 2020, 9:45pm


Newer therapies have led to a boost in the number of patients with relapsed or refractory multiple myeloma (R/R MM) who are prescribed triplet regimens. As that shift has occurred, death rates appear to have dropped.

Flawed Racial Assumptions in eGFR Have Care Implications in CKD

October 25th 2020, 6:45pm


The use of estimated glomerular filtration rate (eGFR) equations in assessing chronic kidney disease (CKD) for Black patients may lead to underdiagnosis and undertreatment, according to a nephrologist speaking at Kidney Week.