Leukemia and Lymphoma

Autoimmune Complications Common in Lymphoid, Myeloid Neoplasms, Says Review

April 23rd 2021, 12:45am

Article

The findings come from the group’s review of over 30 years’ worth of research of the presence of autoimmune cytopenias and autoimmune diseases in lymphoid and myeloid neoplasms.

MDS, CMML Pipelines Inch Closer to Arrival of Targeted Therapies

April 17th 2021, 1:00am

Article

The researchers credit wider availability of molecular testing and better understanding of the diseases for the emerging targeted therapies in development.

Diet, Exercise Enhance Effects of Chemotherapy, Odds of Survival for Youth With ALL

April 9th 2021, 11:00am

Article

Patients who cut their calorie intake by at least 10% and exercised modestly were 70% less likely to have remaining leukemic cells in their bone marrow 1 month after starting chemotherapy, according to results of an early study.

Emerging Options May Help Address Challenges With Traditional BTK-Inhibitor Treatment in Lymphomas

April 3rd 2021, 3:30pm

Article

Reversible Bruton tyrosine kinase (BTK) inhibitors may play a key role in treatment when it comes to addressing resistance stemming mutations in the active site (Cys481) that emerge from treatment with irreversible BTK inhibitors.

Differentiating Between MCL, DLBCL May Require Additional Testing, Case Study Says

April 3rd 2021, 10:30am

Article

Classical mantle cell lymphoma (MCL) and 2 aggressive variants exhibited similar rates of negativity for the CD5 marker, but further testing may be needed in certain cases to avoid misdiagnosis with diffuse large B-cell lymphoma (DLBCL).

What We’re Reading: COVID-19 Vaccine in Adolescents; New AML Drug Approval; Pediatric Respiratory Illness Levels Drop

March 31st 2021, 2:24pm

Article

Pfizer/BioNTech’s COVID-19 vaccine appears to be 100% effective at preventing adolescent infections; Vyxeos approved for pediatric secondary acute myeloid leukemia (AML); study results show a 62% drop in pediatric respiratory illness over the past year.

Medicare Patients With CLL Continue to Face High Costs Related to AEs

March 24th 2021, 9:07pm

Article

More than two-thirds of patients with chronic lymphocytic leukemia (CLL) survived at least 2 years but were highly susceptible to adverse events (AEs), in a recent study.

Reasons for COVID-19 Vaccine Hesitancy in Patients With Blood Cancer Are Complex

March 19th 2021, 8:20pm

Article

A survey released this month of US patients with blood cancers shows a somewhat surprising level of hesitancy about receiving a COVID-19 vaccine, but because patients with cancer were not included in clinical trials, the situation for this population is somewhat nuanced.

Allo-SCT, MRD Negativity Associated With Better Outcomes in AML With Certain Mutations

March 15th 2021, 6:38pm

Article

Study findings shed a light on the role of minimal residual disease (MRD) status and type of postremission therapy in the prognosis of patients with intermediate-risk acute myeloid leukemia (AML) who do not have FLT3-ITD, NPM1, and biallelic CEBPA mutations.

Using WGS to Improve Genomic Profiling in Patients With Blood Cancers

March 12th 2021, 5:30pm

Article

Whole-genome sequencing (WGS) is at least as accurate as conventional tests when it comes to genomic profiling in patients with acute myeloid leukemia and myelodysplastic syndromes.