Leukemia and Lymphoma

Prior Malignancy Linked to Risk of Secondary Malignancy in Follicular Lymphoma

October 29th 2020, 4:00am


Previous research has found a link between a prior malignancy and secondary primary malignancy risk in patients with multiple myeloma. A new study suggests a similar association in follicular lymphoma.

Case Report Suggests Nivolumab Is Effective in Burkitt Lymphoma

October 26th 2020, 9:00pm


A 72-year-old patient with Burkitt lymphoma was successfully treated with nivolumab after standard-of-care chemotherapy failed.

Dr Michael Green Discusses Understanding Patient Response to CAR T-Cell Therapy

October 23rd 2020, 2:30pm


Chimeric antigen receptor (CAR) T-cell therapy does not always lead to a durable response, and we are trying to figure out why, noted Michael R. Green, PhD, University of Texas MD Anderson Cancer Center.

Review Lays Out the Tough Task of Discerning T-cell Prolymphocytic Leukemia

October 21st 2020, 2:45pm


T-cell prolymphocytic leukemia is rare and shares many features with other conditions. A new review article helps explain some of the tactics physicians can use to correctly identify it.

Pembrolizumab Expanded to Treat Relapsed, Refractory cHL in Adults, Children

October 17th 2020, 4:30pm


It is the first PD-1 inhibitor to be approved to be used as a monotherapy for the treatment of adult and pediatric patients with relapsed or refractory (R/R) classical Hodgkin lymphoma (cHL).

MRD Negativity Indicative of Improved OS, DFS in AML, Study Says

October 15th 2020, 10:45am


Based on the findings, the researchers are arguing that minimal residual disease (MRD) should be considered as a clinical trial endpoint.

Dual US, China Approval Process for Zanubrutinib Shows Regulatory Differences

October 7th 2020, 6:00pm


The process of approving a new therapy for relapsing and/or remitting mantle cell lymphoma therapy got off to a faster start in China, but United States regulators caught up and approved the drug first.

Case Report: Ibrutinib Might Protect Against Acute Lung Injury in Patients With CLL, COVID-19

October 2nd 2020, 4:00pm


A patient with chronic lymphocytic leukemia (CLL) was continued on ibrutinib even after developing severe coronavirus disease 2019 (COVID-19). He successfully overcame the infection.

HSCT Viable for Children With Nonremission Acute Lymphoblastic Leukemia

September 30th 2020, 3:00pm


Research into children and adolescents with nonremission acute lymphoblastic leukemia (ALL) has been sparse, but a new analysis suggests that allogeneic hematopoietic stem cell transplantation is a good fit for some patients.

TKI Leads to Superior Outcomes in ALL With an ABL-Class Fusion, Study Says

September 23rd 2020, 8:00pm


Patients with acute lymphoblastic leukemia (ALL) who have an ABL-class fusion had better outcomes than a control group when treated with tyrosine kinase inhibitors at their first relapse, according to a new study.