Leukemia and Lymphoma

Obesity Likely to Adversely Affect Survival Among Patients With ALL

January 26th 2021, 11:15pm


Higher mortality rates were seen among patients with acute lymphoblastic leukemia (ALL) who were considered obese, in a recent study of patients treated at Mayo Clinic.

ALL Survival Gap Persists Between Black, White Children

January 22nd 2021, 10:51pm


Despite outcome improvements for acute lymphoblastic leukemia (ALL), mortality rates remain high, with significant survival disparities seen between Black and White children.

Leukemia Survival Likely Not Affected by Diabetes, Hemoglobin A1C

January 21st 2021, 8:56pm


Research findings from Mayo Clinic investigators demonstrate that diabetes did not increase the risk of death among patients with acute or chronic myeloid leukemia.

Likely Determinants of Successful TKI Treatment Stoppage Identified in CML

January 16th 2021, 2:45pm


Tyrosine kinase inhibitor (TKI) therapy enables patients with chronic myeloid leukemia (CML) to reach life expectancies equivalent to the general population and treatment-free remission, but quality of life can deteriorate with treatment.

What We’re Reading: Abortion Pill Requirement Reinstated; Open Enrollment Numbers Released; Neupogen Safety Info Updated

January 13th 2021, 3:38pm


The Supreme Court reinstates the requirement on in-person pickup of pregnancy-ending medications; CMS releases numbers on 2020’s final week of Marketplace open enrollment; the FDA updates safety information for filgrastim (Neupogen).

Possible New Association Found Between MRD and PFS, OS Among Patients With Mantle Cell Lymphoma

January 7th 2021, 7:10pm


A recent meta-analysis appearing in Journal of Cancer indicates a connection between minimal residual disease (MRD)–positive status and worse progression-free survival (PFS) and overall survival (OS) following induction and consolidation therapies.

Azacitidine Shown to Improve Overall, Relapse-Free Survival in Older Adults With AML

January 5th 2021, 7:53pm


Older adults with acute myeloid leukemia (AML) saw increased overall and relapse-free survival, as well as preserved quality of life, following oral administration of 300-mg azacitidine.

Dr Michael Green: Further Research Is Needed to Better Understand CAR T-Cell Exhaustion

January 2nd 2021, 12:45pm


Chimeric antigen receptor (CAR) T-cell exhaustion likely stems from chemotherapy prior to transplant, noted Michael R. Green, PhD, University of Texas MD Anderson Cancer Center.

Small Study Shows Ruxolitinib Helps Severe Steroid-Refractory CRS in Patients With B-ALL

December 30th 2020, 3:00pm


A small pilot study could point the way to a new option for patients with B-cell acute lymphoblastic leukemia (B-ALL) who experience cytokine release syndrome (CRS) that cannot be cured with the standard therapy.

Top 5 Most-Read Leukemia and Lymphoma Articles for 2020

December 24th 2020, 1:00pm


Readers favored news about ibrutinib, the first chimeric antigen receptor (CAR) T-cell therapy in mantle cell lymphoma, and the effect of the pandemic on patients with chronic lymphocytic leukemia.