Ide-Cel Shows Benefit vs Standard Regimens in Heavily Pretreated R/R Multiple Myeloma
Idecabtagene vicleucel (ide-cel) led to significantly longer PFS and better therapy responses than standard regimens for patients with triple-class–exposed relapsed and refractory multiple myeloma.
Prurigo Nodularis Improves Following Treatment With Dupilumab
March 30th 2023Despite the approval of dupilumab (Dupixent) in September 2022, there is an ongoing dearth of clinically effective treatments for prurigo nodularis, prompting the present investigation of the monoclonal antibody for the chronic inflammatory skin condition.
Bridging the Gap in Health Care Inequities: Considerations in Treatment Selection: Part 1
March 30th 2023In part 1 of this 2-part series on health equity in the treatment of psoriasis, Ryan Haumschild, PharmD, and Bryan Buckley, DrPH, discuss how providers can address disparities in care, specifically with race, cultural, and ethnic backgrounds in mind.
Immunotherapy for NSCLC Safe in Elderly Patients, but More Research Needed
A review based on an expert panel discussion highlights a need for the inclusion of older patients in studies of immune checkpoint inhibitors for the first-line treatment of advanced non–small cell lung cancer (NSCLC).
Pembrolizumab Receives Full Approval for Select Patients With MSI-H or dMMR Solid Tumors
The FDA has granted full approval to pembrolizumab for the treatment of some patients with unresectable or metastatic microsatellite instability–high (MSI-H) or mismatch repair–deficient (dMMR) solid tumors that have progressed following previous treatment.
CVD Outcomes Investigation Highlights Need for More, Better Data on SDOH
March 29th 2023This study of the public health landscape in New York City investigated the interplay between social determinants of health (SDOH), chronic health conditions, and inequities in social factors, with a focus on cardiovascular disease (CVD).
Ten states remain that have not expanded Medicaid and they are unlikely to do so; FDA was aware of contaminated infant formula months before the most recent recall; Sen. Tammy Duckworth asks the Federal Trade Commission to investigate AmeriSourceBergen over its distribution practices around the brand-name of mifepristone (Mifeprex).