
Opinion|Videos|October 21, 2024
Factors Impacting Use of HER2 Therapies for NSCLC
Key Takeaways
- Barriers to HER2-directed therapies include high costs, limited insurance coverage, and stringent prior authorization requirements, impacting patient access and treatment initiation.
- Providers prioritize clinical outcomes like progression-free survival and overall response rates, which may not align with payer focus on cost-effectiveness.
Panelists discuss how payer perspectives and access challenges impact the utilization of HER2-directed therapies in NSCLC, examining barriers to treatment initiation and persistence, aligning provider and payer priorities in outcome assessment, the role of real-world evidence in decision-making and policy formation, and strategies for collaborative efforts between stakeholders to balance equitable access with cost management.
Advertisement
Episodes in this series

Video content above is prompted by the following:
Analyze payer perspectives and access challenges related to HER2-directed therapies in NSCLC.
- (Kim) What are potential barriers to starting and/or persisting on HER2-directed therapies for NSCLC?
- (Bazhenova) Which outcomes do providers find most important in clinical practice, and how do these align with the outcomes payers prioritize when assessing the value of these therapies?
Advertisement
Related to this article

SaTScan detects an acute HCV outbreak cluster in California, showing the potential of automated surveillance, though real-time testing is needed.

Genetic analysis finds 125 loci shared by insomnia and CRP, with Mendelian randomization favoring an effect from insomnia liability to inflammation.

Proinflammatory diets were tied to higher mortality in MASLD and MetALD, whereas antioxidant-rich diets tracked with better survival.

An analysis finds distinct adverse event reporting patterns across immunosuppressive regimens, highlighting the need for tailored safety monitoring.

Sjögren disease involves far more than dry eyes and mouth, and variable symptoms plus multispecialty testing delay diagnosis, says Steven Carsons, MD.

Early MASH risk stratification, drug choice, and aligned coverage could improve outcomes, explained Zobair Younossi, MD.

These phase 3 EXCALIBER-RRMM findings build on earlier MRD-negative complete response results supporting FDA approval of the iberdomide-based regimen.
Advertisement
Advertisement


