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The Nature letter published results showing that the monoclonal antibody targeting PD-1 had antitumor activity, but more importantly, the response was greater in patients overexpressing the PD-L1 receptor, thereby opening the doors for targeted therapy.

HHS is collaborating with the nation's largest pharmacies to encourage enrollment through the Health Insurance Marketplace at thousands of locations across the country.

Gilead Sciences' hepatitis C drugs Sovaldi and Harvoni are the poster children for out-of-control drug costs, but competition from AbbVie's drug may place downward pressure on these prices.

Single-payer health insurance-the only coverage option less popular among conservatives than Obamacare-suffered a setback last week, and it could be fatal.

Republican Governor Bobby Jindal moved quickly to privatize 6 public hospitals with advanced lease payments, and he set up a prescription reimbursement schedule without prior approval from CMS. The agency signed off on privatization but rejected both financial pieces this week, which could leave Louisiana's next governor with a budget shortfall.

San Diego County is doing much better than the national average at reducing readmissions to hospitals, yet nearly all their eligible hospitals are being penalized by Medicare's hospital readmissions penalty program.

Researchers at Stanford University found that when CMS stopped paying for 2 preventable, hospital-acquired conditions in particular, the incidence of the conditions dropped 35% in the Medicare population.

Consumers, administrators, primary care physicians and specialists all agree: they do not think that the healthcare system is on the right track, according to a study from Booz Allen Hamilton and Ipsos Public Affairs.

Marketplace health insurance premiums across the nation did not increase from 2014 to 2015. However, while the overall costs were flat, some states did see substantial average premium increases, which were offset by declines in other states.

The FDA will recommend in 2015 to lift the lifetime ban on blood donations from gay and bisexual men. However, the agency will keep in place a one-year ban after homosexual activity.

The Obama administration's top Medicaid official, who negotiated tough terms with states seeking to expand the program under the health law, is stepping down.

Anthem, Inc, increased its managed care footprint in the state of Florida. On Monday, the company has entered into an agreement to acquire Simply Healthcare Holdings, Inc.

Nearly half of the patients who had access to electronic medical records withheld clinically sensitive information from some or all of their healthcare providers, according to a new study.

Comprehensive care compared with usual care for high-risk children with chronic illness reduced total hospital and clinic costs as well as illnesses, according to a new study in JAMA.

The Ebola outbreak exposed some serious gaps in the nation's ability to manage severe infectious disease threats with half of the country scoring low on key indicators related to preventing, detecting, diagnosing, and responding to outbreaks.

CMS' Sean Cavanaugh announces in a blog post that 89 newcomers will participate in 2015. But ACOs remain a work in progress, with rule changes on the way and some discussion about whether these entities are assuming enough risk or dampening competition in certain markets.

The most important case since the Supreme Court upheld the constitutionality of the Affordable Care Act will determine the law's ability to function in states without their own exchanges.

Florida's Republican Governor, Rick Scott, tried and failed to expand Medicaid in 2013. Now, a coalition of hospital, business, and community leaders are advocating for private option-style expansion. CMS will have to decide how far it is willing to bend before President Obama leaves office.

3.0 Credits - CME/CPE | Expires 12/15/2015

3.0 Credits - CME/CPE | Expires 12/15/2015

The American Society of Clinical Oncology called for greater access to and education about phase I clinical trials, the first-in-human studies of new agents designed to fight cancer.

The approval was based on the results of a clinical trial that demonstrated improved PFS in patients on lanreotide. While the median PFS in the placebo arm was 16 months, patients in the lanreotide arm had not yet reached median PFS at the time of analysis, and it was anticipated to extend beyond 22 months.

Superspreaders, who account for roughly 20% of the population, are more contagious than others and transmit about 80% of certain diseases, The Wall Street Journal reports.

The FDA offered up an early retrospective of the 2014 year of approvals Friday with a rundown the regulator feels pretty good about.

A new study from the Workers Compensation Research Institute found evidence that physician dispensing encouraged some physicians to unnecessarily prescribe strong opioids.

A new study in Hepatology highlights the need to raise awareness among healthcare professionals and at-risk populations about appropriate hepatitis C testing, referral, support, and care.

Although Virginia Gov Terry McAuliffe failed to pass a Medicaid expansion plan during his first year in office, the governor's health secretary has indicated that the fight will begin again.

The National Institute for Health and Care Excellence has issued draft guidelines on using the drug in prostate cancer patients.

More than 700 hospitals will be penalized in fiscal year 2015 as a result of poor scores in CMS' Hospital-Acquired Condition (HAC) Reduction Program.

The falling uninsured rate among all racial/ethnic groups under current Medicaid expansion decisions will narrow coverage differences between whites and all minority groups except for blacks, according to a report from the Urban Institute.