Article

Lilly's Glyxambi, First-in-Class Combination Pill, Approved for T2DM

The dual inhibitor tablet, a combination of an SGLT-2 inhibitor and a DPP-4 inhibitor, is expected to stimulate the pancreas to produce more insulin and stimulate the liver to produce less glucose, and also prevent glucose reabsorption.

The FDA has approved Glyxambi® (empagliflozin/linagliptin) tablets, from Boehringer Ingelheim Pharmaceuticals, Inc. (BIPI) and Eli Lilly and Company, as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes (T2D) when both empagliflozin and linagliptin are appropriate treatments.

Glyxambi is not recommended in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis. Glyxambi has not been studied in patients with a history of pancreatitis, and it is unknown if using Glyxambi increases the risk of developing pancreatitis in these patients.

Link to the complete press release by Eli Lilly: http://bit.ly/1wXXreO

Newsletter

Stay ahead of policy, cost, and value—subscribe to AJMC for expert insights at the intersection of clinical care and health economics.

Related Videos
dr jennifer green
dr jennifer green
dr ken cohen
dr ian neeland
Yael Mauer, MD, MPH
Pregnant Patient | image credit: pressmaster - stock.adobe.com
Diana Isaacs, PharmD
Beau Raymond, MD
Robert Zimmerman, MD
Beau Raymond, MD
Related Content
AJMC Managed Markets Network Logo
CH LogoCenter for Biosimilars Logo