Highlighting the latest ophthalmology-related news reported across MJH Life Sciences™.
Highlighting the latest ophthalmology-related news reported across MJH Life Sciences™.
Ophthalmologic Bevacizumab Formulation One Step Closer to FDA Approval
This week, Outlook Therapeutics announced positive clinical and highly significant top-line results from the phase 3 NORSE TWO safety and efficacy trial comparing bevacizumab with ranibizumab, sold as Lucentis, in the treatment of wet age-related macular degeneration (AMD).
As reported by Ophthalmology Times®, successful completion of the trial served as the final step needed in the clinical evaluation of bevacizumab to submit a Biologics License Application (BLA) to the FDA. These results add to the positive top-line results reported in 2 clinical trials earlier this year of bevacizumab, a full-length, humanized anti-vascular endothelial growth factor (VEGF) biosimilar for the treatment of wet AMD.
Outlook Therapeutics announced plans to submit a BLA in the first quarter of 2022. If approved, bevacizumab would become the first ophthalmologic formulation of bevacizumab to treat retinal conditions.
The originator drug, Avastin, is used off label currently for wet AMD.
Long COVID-19 Linked With Corneal Nerve Damage
Findings of an observational study suggest adverse events related to long COVID-19 may be detectable in the eyes of patients via nerve damage in the cornea and increased dendritic cells, according to Modern RetinaTM.
Examining patients through corneal confocal microscopy (CCM), those with neurological symptoms 4 weeks after acute COVID-19 exhibited lower corneal nerve parameters than controls. Moreover, patients with more severe cases of COVID-19 typically presented with greater corneal nerve damage.
However, these findings were observed in a small cohort and they could not confirm whether the virus caused the corneal abnormalities in patients. Pending further research on CCM, researchers noted that it could be used to objectively identify patients with long COVID-19, which affects up to 30% of patients after recovering from acute COVID-19 infection.
United Nations Adopts First-Ever Resolution on Vision
Seeking to improve access to eye care worldwide, the United Nations (UN) General Assembly announced the approval of its first-ever resolution on vision, called “Vision for Everyone,” which will be sponsored by Bangladesh, Antigua and Ireland, and co-sponsored by over 100 countries.
As reported by Ophthalmology Times®, the resolution was adopted late last month by the UN and will commit the organization to improving vision for 1.1 billion people living with preventable vision loss by 2030.
Encouraging all 193 member nations to adopt a federal approach to eye care, the UN resolution is also urging international financial institutions and donors to provide targeted financing to tackle the rising impact of vision loss on economic and social development.
Dr Kathryn Lindley Explains the Importance of Cardio-Obstetrics in Fellowship Programs
December 5th 2023Kathryn Lindley, MD, FACC, Vanderbilt University Medical Center, talks about why it’s important to incorporate cardio-obstetrics training into cardiovascular disease fellowship programs.
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Oncology Onward: A Conversation With Thyme Care CEO and Cofounder Robin Shah
October 2nd 2023Robin Shah, CEO of Thyme Care, which he founded in 2020 with Bobby Green, MD, president and chief medical officer, joins hosts Emeline Aviki, MD, MBA, and Stephen Schleicher, MD, MBA, to discuss his evolution as an entrepreneur in oncology care innovation and his goal of positively changing how patients experience the cancer system.
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Insufficient Data, Disparities Plague Lung Cancer Risk Factor Documentation
September 24th 2023On this episode of Managed Care Cast, we speak with the senior author of a study published in the September 2023 issue of The American Journal of Managed Care® on the importance of adequate and effective lung cancer risk factor documentation to determine a patient's eligibility for screening.
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What We’re Reading: Affordable Home Care; Mycoplasma Infections Rise; Opioid Crisis Settlement
December 4th 2023Families struggle to find affordable, reliable home health aides; reports of increased pediatric pneumonia cases; legal battle ensues over Purdue Pharma’s bankruptcy settlement.
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SABCS 2023 Sessions Touch on "Every Aspect of Breast Cancer"
December 4th 2023The 46th annual San Antonio Breast Cancer Symposium will take place December 5-9, with new and experienced attendees able to choose and learn from a schedule overflowing with the latest developments in breast cancer science and research.
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