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Treating Hyperglycemia Early Could Reduce CV Risks, Study Shows
Published in Diabetes Care, the study found that earlier detection, and importantly, initiating treatment early, can reduce cardiovascular risks.
A study published in Diabetes Care found that earlier detection, and importantly, initiating treatment early, can reduce cardiovascular risks.
The authors retrospectively analysed patient data from a large European study of people 40 to 69 years old without known diabetes who were screened and treated for the condition. While in the original study, some patients with hyperglycemia were treated intensively while others were given standard treatment, no difference in cardiovascular outcomes or death was documented 5 years later. To predict outcomes in thes same population if screening had been delayed by another 3 to 6 years, the researchers of the current study used a simulation model.
The results: a 3 year delay could have resulted in 11% of people experiencing a heart problem within 5 years, compared to about 8% when screening wasn't delayed. If screening was delayed by 6 years, they estimated that about 13% of participants would experience a heart problem over the 5 years.
Complete article on Medscape: http://wb.md/1HPL36j
Real-World Study Reveals Key Insights into DLBCL Treatment Patterns, Outcomes
April 18th 2024A recent study offers valuable insights into the characteristics, treatment patterns, and outcomes of diffuse large B-cell lymphoma (DLBCL) in patients across different lines of therapy, providing a look into the landscape of DLBCL management.
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Pegcetacoplan for PNH More Cost-Effective Than Anti-C5 Monoclonal Antibodies
April 18th 2024A cost-utility analysis conducted from the perspective of the Italian health system found that pegcetacoplan was more effective and less costly than 2 complement 5 (C5) inhibitors for the treatment of paroxysmal nocturnal hemoglobinuria (PNH).
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Many Patients With Psoriasis in Clinical Trials Experience Nocebo Effects, Study Finds
April 18th 2024Half of patients exposed to placebo in clinical trials experienced adverse events (AEs), which may be partially explainable by nocebo effects, according to a recent review and meta-analysis.
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Low-Volume Hospitals Had Higher Reoperation Rate, Postoperative Complications in CRC
April 18th 2024Patients opting for elective colorectal surgery to address colorectal cancer (CRC) could have different rates of reoperation and postoperative complications based on the size of the hospital.
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