V. Silverstein, MD


Novel Approaches for the Prevention and Treatment of Inflammatory Bone Loss

September 13, 2014

Current novel therapeutics for the prevention and treatment of bone loss in patients with inflammatory joint disease target cytokines and other inflammatory mediators. Mesenchymal stem cell therapy is a compelling new treatment currently being studied in clinical trials.

Preventing Bone Erosion By Effectively Treating Rheumatoid Arthritis

September 13, 2014

Bone erosion, a common side-effect of rheumatoid arthritis, can be prevented by using a combination of close patient monitoring and individualized therapeutic regimens that include agents to block cytokines, block osteoclasts, or target abnormal cellular reactions.

The Pathophysiology of Inflammatory Bone Loss

September 13, 2014

Inflammatory bone loss is caused by a complex pathway that begins with inflammatory cell production of cytokines, progresses to abnormal bone absorption, and culminates in the destruction of joints, bone fractures, and patient debility.