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Neulasta Onpro: A Coup de Grâce?With the rapid decline in average sales price of reference pegfilgrastim products due to biosimilar competition, health care institutions and payers may grapple with coverage of Neulasta Onpro.
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FDA Fast Tracks BCMA-Targeted CAR T-Cell Therapy for R/R Multiple MyelomaThe FDA has granted a fast track designation to CB-011, a CRISPR-edited allogeneic CAR T-cell therapy developed by Caribou Biosciences, for the treatment of patients with relapsed/refractory multiple myeloma.
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The Relationship Between the Follow-up to Discharge Ratio and Length of StayThe objective was to evaluate the correlation between the follow-up to discharge ratio and average length of stay.
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Contributor: For Better or Worse, Inflation Isn’t New to Health InsurersIn this column, a health insurance executive discusses 2 ways to address rising inflation, including moving past the traditional fee-for-service payment model.
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Frontline Pembrolizumab Plus Trastuzumab/Chemotherapy Improves PFS in HER2+ Gastric/GEJ CancerAdding pembrolizumab to combination of trastuzumab and chemotherapy improved progression-free survival vs placebo plus trastuzumab and chemotherapy in the first-line treatment of patients with metastatic HER2-positive gastric or gastroesophageal junction (GEJ) cancer.
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Pharmacist-Led Review of Empagliflozin and Ertugliflozin Following Formulary UpdateManagement of empagliflozin and ertugliflozin may be suboptimal following an insurance carrier’s formulary updates. Pharmacists may improve the management.
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Predicting Hospital Readmission in Medicaid Patients With Diabetes Using Administrative and Claims DataA statistical model based entirely on claims data can accurately predict 30-day hospital readmission in Medicaid patients with diabetes.
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Hospital Performance in a Statewide Commercial Insurer Episode-Based Incentive ProgramSome hospitals were able to outperform others in a commercial insurer episode-based incentive program, but there was little evidence of global reductions in episode spending.
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COVID-19 Control in the United States: The Case for MaskingIn the control of COVID-19, the future perfect of the vaccine should not be the enemy of the present good, which is masking.
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Identifying Complex Patients Using Adjusted Clinical Groups Risk Stratification ToolIn this study, the authors developed a method for use in primary care to identify a group of patients with complex care needs using Aggregated Diagnosis Groups.
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ASRS 2023: Intended vs Actual Treatment Intervals Between Intravitreal Anti-VEGF Injections: Effects of Treatment DaysIn the study, researchers found that nearly one-quarter of anti-VEGF injections were received at least 1 week later than intended.
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A Case-Control Study of Length of Stay OutliersLength of stay outliers are associated with hospital-acquired infections, complications, and discharge to facility, as opposed to nonmodifiable risk factors like age and comorbidities.
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Social Determinants of Health Score: Does It Help Identify Those at Higher Cardiovascular Risk?Calculating a social score is feasible and it predicts cardiovascular outcomes. In order to do this, institutions have to collect social determinants of health.
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Predicting Drug-Drug and Drug-Gene Interactions in a Community Pharmacy PopulationThe probability of drug interactions increases when genetic polymorphisms are considered, indicating that pharmacogenetic assessment may be useful in predicting the presence and severity of interactions.
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Changes in Electronic Notification Volume and Primary Care Provider BurnoutPrimary care provider burnout was analyzed before and after a national initiative to optimize the electronic health record inbox notification system at the Veterans Health Administration.
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Projected US Savings From Biosimilars, 2021-2025Projected savings from biosimilars from 2021 to 2025 were $38.4 billion vs conditions as of quarter 4 of 2020 and were driven by new biosimilar entry. Savings were $124.5 billion under an upper-bound scenario.
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Hypoglycemia Upon Hospital Admission From Long-term Care: Health Care Resource UseThis analysis of a hospital billing database describes inpatient length of stay, intensive care unit length of stay, comorbidities, and costs for patients with diabetes after admission with hypoglycemia from long-term care or home.
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Psychological Safety and Use of Incident Reporting SystemsIncident reporting systems, which are often computer based and require no in-person interactions, can enable health care staff who perceive low psychological safety to speak up.
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Provider and Patient Insights Into the Cancer Care JourneyA survey was conducted to determine opportunities to aid primary care providers and patients in the difficult journey of an oncology patient.
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Machine Intelligence for Early Targeted Precision Management and Response to Outbreaks of Respiratory InfectionsThis paper evaluates novel machine intelligence to predict patients at risk of severe respiratory infections and recommend postacute care providers likely to reduce infection risk.
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Community Health Workers’ Critical Role in Trust Building Between the Medical System and Communities of ColorThe authors interrogate elements of routine medical practice in New York City to argue for reforms of hospital culture through relational trust-building capabilities of community health workers.
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The Role of Race, Ethnicity, and Language in Care TransitionsDiverse patients experience disparities in care transitions. A survey of 224 patients showed differences by race, ethnicity, and language in technology access and in patient worries post discharge.
