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Real-World Value of Direct-Acting Antivirals for Hepatitis C at Kaiser Permanente Southern CaliforniaThis analysis demonstrates value and innovation of direct-acting antivirals for the treatment of chronic hepatitis C in the US Kaiser Permanente health system.
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Promoters of Therapeutic Inertia in Managing Hypertension: A Consensus-Based StudyThe authors identified consensus-based promoters of clinical inertia in managing hypertension. Policy makers should address these promoters to improve health-related outcomes in hypertension.
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Mental Health Diagnoses and Services Utilization Vary by Wage LevelInsured lower-wage employees had lower prevalence of mental health conditions but greater severity, with more hospital admissions and emergency department visits than high-wage employees.
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Oncologists’ Perceptions and Utilization of US Therapeutic Oncology BiosimilarsBiosimilar use in clinical practice is determined by oncologists’ perceptions of and willingness to prescribe them. The authors investigated US oncologists’ perceptions and use of biosimilars.
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The Patient PerspectivePanelists discuss how patient perspectives on new therapies center around clinically meaningful outcomes and survival while balancing individual risk tolerance, with some patients willing to accept higher risks for potentially transformative treatments in devastating diseases.
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Telehealth Insights From an Integrated Care SystemExperiences from a large, integrated, value-based health system suggest that telehealth can be an effective care delivery approach. Public policies can improve telehealth access and care.
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Reply to “Industry-Informed Perspectives on the Benefits of Rideshare-Based Medical Transportation”The authors of “Rideshare Transportation to Health Care: Evidence From a Medicaid Implementation” respond to a letter to the editor.
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Screening for Health Literacy, Social Determinants, and Discrimination in Health PlansThis study provides insight on the experiences of patients of a national health plan with 2 structural determinants of health—health care discrimination and health literacy—and how those interact with social determinants of health and patient demographics.
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Access Denied: CMS’ Action Hurts Patients With Cancer in Rural AmericaCMS rules hindered the access of rural patients with cancer to medically integrated pharmacies in 2023. The authors discuss the impact on equity in health care, emphasizing the need for regulatory change.
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Impact of Telemedicine Use on Outpatient-Related CO2 Emissions: Estimate From a National CohortTelemedicine was associated with a monthly avoidance of greenhouse gas emissions equivalent to the emissions of 61,255 to 130,076 passenger vehicles.
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Hospital Partnership and Patient Outcomes Among Postacute Patients With StrokeThis article explores the patient-sharing relationships between acute hospitals and postacute hospitals and how these relationships influence patient discharge outcomes.
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Outcomes in Patients With IBD Stratified by Risk of Disease ProgressionThis study validates criteria to identify patients with inflammatory bowel disease (IBD) at risk of worsening disease who may benefit from early treatment with advanced therapies.
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Incidence and Cost of Potentially Avoidable Emergency Department Visits for UrolithiasisThis study characterizes the incidence and associated factors of urolithiasis-related emergency department visits that are potentially preventable with appropriate ambulatory care and calculates their cumulative costs.
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Frequency of Condomless Sex Among Women Using Reversible Methods of ContraceptionA substudy of the Evidence for Contraceptive Options and HIV Outcomes trial, which compared 3 highly effective, reversible methods of contraception, concluded that women assigned either a copper intrauterine device or the levonorgestrel implant may have had condomless sex more frequently than women assigned to intramuscular depo-medroxyprogesterone acetate.
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How Do Primary Hospitals Enact Early Response to the Relaxation of COVID-19 Prevention and Control Measures? The Experience From Chengdu, ChinaThis article examines how primary hospitals in Chengdu, China, responded to the relaxation of COVID-19 prevention and control measures in December 2022.
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An Accelerated Hospital Observation Pathway to Reduce Length of Stay for Patients With COVID-19For select patients hospitalized due to COVID-19, an academic urban hospital implemented an observation pathway that incorporated mobile health technology, reducing hospital length of stay by more than 2 days.
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Implementation of Early Follow-up Care After Heart Failure HospitalizationAn early heart failure follow-up intervention succeeded in increasing referral to and completion of cardiology appointments within 7 days of discharge. The intervention was associated with lower risk of 30-day all-cause emergency department visits, all-cause hospitalizations, or death.
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Medicare Advantage Coverage Restrictions for the Costliest Physician-Administered DrugsFour large Medicare Advantage insurers manage access to expensive physician-administered drugs with a combination of prior authorization, step therapy, and Part D formulary design.
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Flash CGM Associated With Event Reduction in Nonintensive Diabetes TherapyAnalysis of the MarketScan database showed a strong association between flash continuous glucose monitoring (CGM) use and significant reductions in diabetes-related events and hospitalizations in a cohort of 10,282 adults with type 2 diabetes.
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Delays in Detection and the Impact on Access to Targeted TherapyPanelists highlight that despite established guidelines, delays and gaps in molecular profiling—especially for KMT2A rearrangements—persist due to report complexity, misinterpretation, and misconceptions about patient eligibility, underscoring the urgent need for improved provider education, expert collaboration, and comprehensive testing to ensure accurate diagnosis, optimal treatment selection, and better patient outcomes in acute myeloid leukemia (AML).
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Management of Procalcitonin Test Overuse in an Emergency Department Through a Computer AlgorithmProcalcitonin test demand from the emergency department is growing, necessitating the implementation of strategies to address overuse. Successful interventions must be based on information technology.
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Association of Physician Coordination With Interfacility Transfer Acceptance TimelinessThe authors reviewed physician-to-physician conversations during emergency transfer of patients with ST-segment elevation myocardial infarction and found that higher-quality physician coordination was associated with faster time to acceptance.
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Comparison of Mortality Between Medicare Advantage and Traditional Medicare Beneficiaries With Kidney FailureThe risk-adjusted 1-year mortality rate was not different between Medicare Advantage and traditional Medicare beneficiaries with kidney failure who initiated dialysis.
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Access to Therapy and Future Treatment Directions in Lupus NephritisGerman Hernandez, MD, FASN, FACP, and Ellen Ginzler, MD, MPH, discuss barriers to treatment access in lupus nephritis, and address future directions and unmet needs of the disease.
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Veterans Health Administration Benefit Value Has Little Effect on RelianceRelying on veteran survey responses and novel actuarial data, the authors examine the relationship between benefit value and reliance on the Veterans Health Administration.
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The Promise of Telehealth—a Cautionary TaleImplications of Telehealth Use on the Future of Oncology Care
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Differences in Spending for Diabetes and Multiple Chronic Conditions in Michigan Medicare BeneficiariesDiabetes and multiple chronic conditions increase overall Medicare spending, but spending increases even more in minority beneficiaries compared with White beneficiaries with similar comorbidity combinations.
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A Novel Approach to Attribute Responsible Physicians Using Inpatient ClaimsThe authors propose a novel approach in which physicians’ responsibility for inpatient stays is expressed through physician-specific attribution ratios informed by patient characteristics.
