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Quantifying the Role of Natalizumab in Health and Economic Outcomes in Multiple Sclerosis
David W. Brandes, MS, MD, FAAN; Fadia T. Shaya, PhD, MPH; and Michael W. Pill, PharmD

Quantifying the Role of Natalizumab in Health and Economic Outcomes in Multiple Sclerosis

David W. Brandes, MS, MD, FAAN; Fadia T. Shaya, PhD, MPH; and Michael W. Pill, PharmD
MS poses a significant clinical and financial burden to patients, payers, health systems, and society. As the clinical manifestations of MS progress, the economic and societal burdens also increase. Natalizumab therapy can reduce MS signs, and preliminary economic studies indicate that natalizumab may reduce medical costs as well. While natalizumab itself represents a significant expenditure, the associated reduction in relapse rates and disease progression may reduce overall costs. Additional long-term studies are needed to better quantify the medical and nonmedical costs of natalizumab therapy.

 

Acknowledgment: Editorial support for this manuscript was provided by James Radke.

Author Affiliations: From Hope Neurology (DWB), Knoxville, TN, and University of California, Los Angeles; University of Maryland School of Pharmacy (FTS), Baltimore, MD; and Gemini Healthcare, LLC (MWP), Westbrook, CT.

Funding Source: Financial support for this work, including honoraria, was provided by Biogen Idec.

Author Disclosures: Dr Brandes reports receiving honoraria and lecture fees from and serving as consultant/advisory board member at Bayer, Biogen Idec, EMD Serono, and Teva. Drs Shaya and Pill report no relationship or financial interest with any entity that would pose a conflict of interest with the subject matter of this article.

Authorship Information: Concept and design (DWB, FTS, MWP); analysis and interpretation of data (DWB, MWP); drafting of the manuscript (DWB, FTS, MWP); critical revision of the manuscript for important intellectual content (DWB, FTS, MWP); supervision (FTS); and approval of final version of manuscript (DWB, FTS, MWP).

Address correspondence to: Fadia T. Shaya, PhD, MPH, Associate Professor, University of Maryland School of Pharmacy, 220 Arch St, 12th Fl, Baltimore, MD 21201. E-mail: fshaya@rx.umaryland.edu.

 

 

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