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Roche announced that its phase 3 IMpower150 study determined that the combination of drug atezolizumab (Tecentriq) to bevacizumab (Avastin) with the chemotherapy drugs paclitaxel and carboplatin showed a significant reduction in the risk of disease worsening or death compared to Avastin plus chemotherapy in the first-line treatment of patients with non-small cell lung cancer (NSCLC).

Behavioral testing of adolescents identified 3 distinct subgroups, suggesting there is not a clear-cut explanation for the disorder.

An analysis using mixed quantitative and qualitative methods, as well as site visits to 7 US oncology practices, identified 13 attributes within 5 themes that potentially contribute to high-quality care at a relatively low total cost.

Data from a study of smokers with chronic obstructive pulmonary disease (COPD) indicate that the concentration of eosinophils in the sputum, rather than the blood, is a better predictor of COPD exacerbations and lung function.

A recent study evaluated the treat-to-target strategy by assessing whether patients with early rheumatoid arthritis (RA) who start methotrexate as monotherapy had similar or worse outcomes compared with patients who started with adalimumab plus methotrexate.

VA Secretary David Shulkin wants the private sector to play a larger role in veterans' healthcare; Arizona's Supreme Court ruled in favor of a component to keep the state's Medicaid expansion; Acorda ends drug development of tozadenant for Parkinson's disease.

The Coverage2Control campaign has worked to convince payers of the value of life-saving technology and the need to control out-of-pocket costs.

Most US adults would prefer to find other ways to manage their pain, such as neck or back pain, before taking prescribed pain medication, a Gallup research brief found.

A recent abstract presented at the American Society of Clinical Oncology (ASCO) annual meeting compared 2 risk models for patients with intermediate chemotherapy-induced neutropenia (CIN) risk and compared them to guidelines from ASCO and the National Comprehensive Cancer Network to determine when colony-stimulating factor should be ideally used to prevent CIN. ​​​​​​

Researchers examined the gut microbiome of patients with metastatic melanoma who were being treated with anti–PD-1 immunotherapy, and they determined that patients with a more diverse population of gut bacteria or an abundance of certain types of bacteria were more likely to have their disease controlled for longer.

Federal regulators are asking for information that will get to the bottom of how drug discounting between pharmaceutical companies and health plans affect what seniors pay at the pharmacy counter.

The White House indicated willingness to leave the individual insurance mandate in place in tax reform legislation; California health system Sutter Health was accused of intentionally destroying 10 years of records related to an antitrust lawsuit; and a new study indicates over 1 in 5 patients develops posttraumatic stress disorder in the months after a cancer diagnosis.

With the growing shift to community-based and patient-centered care, the National Quality Forum (NQF) and the Center to Advance Palliative Care (CAPC) have launched initiatives to ensure that patients with serious illness receive safe, effective, and high-quality care. At the same time, professionals in the healthcare industry are highlighting the importance of integrating this type of care into the oncology practice.

This week, the top stories in managed care included new hypertension guidelines lowering the threshold for high blood pressure, Trump nominating a new HHS secretary, and many consumers now have access to less expensive ACA plans.

Recently reported results of a phase 3 study found that patients with psoriatic arthritis (PsA) who received intravenous golimumab (Simponi) had significantly greater improvements in the signs and symptoms of PsA through week 24 than did patients who received placebo.

With an expansion that includes immunotherapy combination treatments, the American Society of Clinical Oncology (ASCO)’s Targeted Agent and Profiling Utilization Registry (TAPUR) Study has now grown to 500 participants and 16 therapies.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

The FDA issued new guidelines to speed up the review process for gene therapies; a new report calculates the potential societal benefits of eliminating the opioid epidemic; and one-third of Americans are unaware that the ACA's open enrollment season has begun.

The first major update since 2003 was announced this week during the 2017 American Heart Association Scientific Sessions.

As part of US Antibiotic Awareness Week and World Antibiotic Awareness Week, the CDC has updated its educational effort to promote safe antibiotic prescribing and use through Be Antibiotics Aware: Smart Use, Best Care. The platform includes information on antibiotic misuse, resources for all audiences, and activity ideas to promote the effort.

Authors of the study found that the mean total, chemotherapy, and physician costs were all lower in community settings compared with hospital-based settings for patients with breast, lung, and colorectal cancer. There were also fewer emergency department visits both 3 and 10 days following treatment.

FDA on Thursday authorized a faster approval path for a next-generation sequencing assay developed at Memorial Sloan Kettering Cancer Center (MSK) that represents both a scientific and regulatory breakthrough at the agency.

A collaboration founded by the American Medical Association (AMA) will bring together organizations like IBM, Cerner, Intermountain Healthcare, the American Heart Association, and the American Medical Informatics Association to improve patient care through a better way to organize and share healthcare information.

Researchers studied tweets from people with ADHD to identify factors like personality and posting frequency, which may hold clues to understanding and treating patients with the disorder.

An analysis digs into whether the FDA really is approving drugs faster under Commissioner Scott Gottlieb, MD; a clinical trial for a Parkinson's disease drug halts enrollment after 5 deaths; and California fines Anthem $5 million for poor response to consumer complaints.

The University of Illinois aimed to improve the time to antibiotic adminstration for patients with febrile neutropenia by implementing a new standard operative protocol.

A mathematical model may help providers better understand which patients will benefit from certain immunotherapy.

Study finds 2 competing opioid treatments have similar outcomes; GOP tax bill includes repeal of the ACA's individual mandate; and a study finds a correlation between screen time and depression in teenage girls.

Medical health research spending in 2017 is likely to increase, primarily due to an additional $2 billion earmarked for the National Institutes of Health, but the long-term outlook for research and development is uncertain. The authors cite the current administration’s calls for large cuts to federal research funding across non–defense-related areas as a potential cause of reduced spending on health research.

Cyclin-dependent kinase 4/6 inhibitors may have proven benefits for treating metastatic breast cancer, but the therapies are associated with hematological toxicities and febrile neutropenia.