Currently Viewing:
Currently Reading
Alemtuzumab Retained Long-Term Safety and Efficacy in Patients With Relapsing-Remitting Multiple Sclerosis of All Ages
June 15, 2019 – Wallace Stephens
Isatuximab Combination Improves PFS in Relapsed, Refractory MM
June 15, 2019 – Samantha DiGrande
Sensory Processing Difficulties Worsen Quality of Life in Children With Migraine
June 15, 2019 – AJMC Staff
Are Daily Corticosteroids Necessary for Mild Asthma? Recent Study Suggests Otherwise
June 14, 2019 – Samantha DiGrande
Exploring Oncology Financial Toxicity, Cost of Care
June 14, 2019 – AJMC Staff
Attending to Psychosocial Concerns for Those With Epidermolysis Bullosa
June 14, 2019 – AJMC Staff
5 Takeaways From the ADA Scientific Sessions
June 14, 2019 – Mary Caffrey
AJMC® in the Press, June 14, 2019
June 14, 2019 – AJMC Staff
This Week in Managed Care: June 14, 2019
June 14, 2019

Any Physical Activity Lowers CVD Risk for Elderly, Study Finds

Jaime Rosenberg
Physical activity, even of a low-intensity, reduces the risk of cardiovascular disease in older adults, according to a study published in The European Journal of Preventive Cardiology. Although the authors found similar associations for individuals under age 55 and individuals aged 55-65, the results were not statistically significant.
Any physical activity (PA) in elderly individuals is beneficial for reducing cardiovascular disease risk, according to a study published in The European Journal of Preventive Cardiology.

The World Health Organization has said that 150 minutes of moderate intensity PA, or 75 minutes of high intensity PA, yields major health benefits, and that any amount of PA leads to health benefits. However, “Current PA guidelines are mainly aimed at middle-aged individuals,” wrote the authors. “It is less well established whether different PA intensities also translate into cardiovascular health benefits in elderly people.”

The authors of the study analyzed data from the EPIC Northfolk prospective population study, which is part of the 10-country collaborative EPIC study. The 24,502 participants of the study, aged 39 to 79, completed a health and lifestyle questionnaire at the baseline survey between 1993 and 1997, participated in a physical examination, and gave blood samples. Standardized measures were also used for body mass index (BMI), blood pressure, and serum total cholesterol. The age of participants was categorized as: under age 55, 55 to 65 years, and over age 65.

Physical activity was measured by a questionnaire that inquired about activities in occupational and leisure time domains, and was categorized into 4 levels: active, moderately active, moderately inactive, and inactive.

A Cox proportional hazards model was used to assess the association between the PA categories and the risk of cardiovascular events in all 3 of the age groups. The median follow-up was 18 years, resulting in a total of 412,954 person-years of follow-up. Of the participants, 4450 (18.2%) experienced a coronary heart disease (CHD) event during follow up, 1231 (5%) experienced a stroke event, and 441 (1.8%) experienced both a CHD and a stroke event.

Results showed that for adults over age 65, the adjusted hazard ratios (HRs) for CVD events were 0.88 (95% confidence interval [CI]; range, 0.77 to 1.02), 0.87 (95% CI; range, 0.77 to 0.99), and 0.86 (95% CI; range, 0.78 to 0.96) for active, moderately active, and moderately inactive participants, respectively, compared to inactive participants.

While there were similar associations for participants under age 55 and participants aged 55 to 65, the results were not statistically significant.

For participants under age 55, the adjusted HRs for CVD were 0.95 (95% CI 0.76–1.18) for active participants, 0.85 (95% CI 0.69–1.05) for moderately active participants, and 1.03 (95% CI 0.84–1.26) for moderately inactive participants, compared to inactive participants.

For participants aged 55-65, the adjusted HRs were 0.84 (95% CI; range, 0.72 to 0.99), 0.99 (95% CI; range, 0.86 to 1.14), and 0.89 (95% CI; range, 0.77 to 1.02) for active, moderately active, and moderately inactive participants, respectively.

“A broader array of public health, healthcare systems, and communities should be involved in helping elderly people to engage in any PA of any level and to reduce a sedentary lifestyle,” concluded the authors.

Copyright AJMC 2006-2019 Clinical Care Targeted Communications Group, LLC. All Rights Reserved.
Welcome the the new and improved, the premier managed market network. Tell us about yourself so that we can serve you better.
Sign Up