Hemophilia: Managing the Cost of Care with a Focus on Patient Outcomes A CE/CME supplement to The American Journal of Managed Care

Faculty

Kenneth A. Bauer, MD

Director

Thrombosis Clinical Research

Hematology-Oncology Division

Beth Israel Deaconess Medical Center

Professor

Department of Medicine

Harvard Medical School

Boston, Massachusetts

Dan R. Dalton, MS, RPh

Program Director

UNC Hemophilia Treatment Center Pharmacy

Division of Hematology/Oncology

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina

Editorial Support

Kim Tran-Kerr, MD

Hitt Medical Writing, LLC

Alpharetta, Georgia

Activity Overview

Hemophilia and its complications are associated with substantial morbidity, and hemophilia ranks as one of the most expensive chronic diseases in the United States. This supplement to The American Journal of Managed Care will provide an epidemiological and clinical overview of hemophilia, discuss current and emerging pharmacotherapeutic strategies, evaluate the burdens of disease, and discuss the importance of involving healthcare professionals and managed care providers in the care of these patients.

Educational Objectives

Upon completion of this activity, participants should be able to:

• Explain the clinical and economic impact of hemophilia in the managed care setting
• Discuss the role of early prophylaxis in preventing long-term complications of hemophilia
• Summarize the efficacy, safety, and cost of newly approved therapies for hemophilia A or B
• Review the role of new therapies in the current hemophilia treatment paradigm and their impact on standards of care

Intended Audience

Managed care clinicians and administrators, including physicians, pharmacists, medical and formulary directors, and other managed care professionals involved in the care of patients with hemophilia.

Release date: March 15, 2015

Expiration date: March 15, 2016

Estimated time to complete activity: 3.0 hours

Type of activity: Knowledge

Medium: Internet-based activity with posttest, evaluation, and request for credit

Fee: Free

Physician CreditAccreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Penn State College of Medicine and Pharmacy Times Office of Continuing professional Education. Penn State College of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation

3.0 AMA PRA Category 1 Credits™

Penn State College of Medicine designates this enduring material activity for a maximum of . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Note: Information about CME credit for this activity is available by contacting Penn State College of Medicine at 717-531-6483 or ContinuingEd@hmc.psu.edu. Reference course # G5743-15-Tfor the online version or G5744-15-R for the print version.

Pharmacy Credit Accreditation Statement

Pharmacy Times Office of Continuing Professional Education is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity is approved for 3.0 contact hours (0.30 CEUs) under the ACPE universal activity number 0290-9999-15-018-H01-P. The activity is available for CE credit through March 15, 2016.

Obtaining Credit:

All participants must read the article, complete the online pretest and posttest achieving a passing score of 70% or higher, and complete an online evaluation and request credit before the activity expires.

Disclosure Policy

According to the disclosure policy of the Penn State College of Medicine, all persons who are in a position to control content are required to disclose any relevant financial relationships with commercial interests. If a conflict is identified, it is the responsibility of the Penn State College of Medicine and Pharmacy Times Office of Continuing Profession Education to initiate a mechanism to resolve the conflict(s). The existence of these relationships is not viewed as implying bias or decreasing the value of the activity. All educational materials are reviewed for fair balance, scientific objectivity of studies reported, and levels of evidence.

The American Journal of Managed Care

Publishing Staff-Jeff D. Prescott, PharmD, RPh, and Ida Delmendo have no relevant financial relationships with commercial interests to disclose.

Penn State College of Medicine

Planning staff and faculty involved in the development and review of this activity have no relevant financial relationships with commercial interests to disclose.

Pharmacy Times Office of Continuing Professional EducationPlanning staff-David Heckard; Maryjo Dixon, RPh; Donna Fausak; and Nathalie Harden have no relevant financial relationships with commercial interests to disclose.

Disclosure of Unapproved/Off-Label Use

The contents of this activity may include information regarding the use of products that may be inconsistent with or outside the approved labeling for these products in the United States. Participants should note that the use of these products outside current approved labeling is considered experimental and are advised to consult prescribing information for these products

The information provided in this CE/CME activity is for continuing medical and pharmacy education purposes only and is not meant to substitute for the independent medical or pharmacy judgment of a physician or pharmacist relative to diagnostic, treatment, or management options for a specific patient's medical condition.

The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of The American Journal of Managed Care, Pharmacy Times Office of Continuing professional Education, and Penn State College of Medicine, or any of the companies that provided commercial support for this CE/CME activity.

For Physician Credit (only): Start Activity

For Pharmacists Credit (only): Start Activity

System Requirements

PC-based participants: Required:

Windows® 7, Vista, XP, 2003 Server or 2000

Macintosh®-based participants:

Required Mac OS® X 10.4.11 (Tiger®) or newer