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Humanistic and Economic Burden of Hepatocellular Carcinoma: Systematic Literature ReviewWorldwide, more than half a million new cases of hepatocellular carcinoma (HCC) are diagnosed annually. The incidence of HCC in the United States is rising with an estimated 31,000 new cases in 2018. Disease prognosis remains poor, with a 5-year survival rate across all disease stages estimated between 10%-20%, and 3% for those diagnosed with distant disease. Although morbidity is significant, especially among patients with advanced-stage disease, limited information exists on the humanistic and economic burden of HCC.
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Colorectal Cancer Screening Use Among Insured Primary Care PatientsColorectal cancer screening use was similar in 2 divergent primary care populations. Colonoscopy was the most frequently used modality; FOBT was used inconsistently.
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Prescribing Trend of Pioglitazone After Safety Warning Release in KoreaThe pioglitazone safety warning issued in South Korea, which recommended prescribing with careful attention among those with high risk of bladder cancer, led to a moderate decrease in pioglitazone users.
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Functional Status and Readmissions in Unilateral Hip FracturesFunctional status is an important predictor of an acute care readmission in patients who have had a unilateral hip fracture.
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Health Insurance Design and Conservative Therapy for Low Back PainThis study examined the association between health insurance design features and choice of physical therapy or chiropractic care by patients with new-onset low back pain.
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Social Determinants of Health Score: Does It Help Identify Those at Higher Cardiovascular Risk?Calculating a social score is feasible and it predicts cardiovascular outcomes. In order to do this, institutions have to collect social determinants of health.
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Distinct Health Care Use Patterns of Patients With Chronic Gastrointestinal DiseasesPatients with complex chronic disease can be grouped by varying propensity for health care continuity patterns, which could be harnessed to personalize health care utilization interventions.
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Primary Care and Communication in Shared Cancer Care: A Qualitative StudyThis qualitative study assesses patient, PCP, and oncologist views on primary care roles in shared cancer care, as well as patterns of communication between physicians.
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Impact of a Physician-Led Point of Care Medication Delivery System on Medication AdherenceA point of care medication delivery system improves medication adherence to cardiovascular medications without increasing costs.
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Risk Stratification for Return Emergency Department Visits Among High-Risk PatientsThe authors examined 2 high-risk classification methods to compare and contrast the patient populations, and to identify the preferred method for predicting subsequent emergency department visits.
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Collaborative Care Before Accountable Care: Achieving Low-Cost, High-Quality Care Through a Regional Collaborative in FloridaAs accountable care organizations proliferate across the nation, delivery systems still struggle to balance quality improvement, cost containment, and migration toward accountable care. This paper describes the phased approach where the University of Florida Health Science Center and Shands Teaching Hospital and Clinics, Inc, and Orlando Health have jointly developed a series of clinical and health services that are of the highest quality and are offered at the lowest cost. The result is a regional collaborative that will be the foundation for a regional accountable care organization, first leveraging clinical core competencies, then moving to a more integrated model.
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Evaluation of Interdisciplinary Geriatric Transitions of Care on Readmission RatesAn interdisciplinary transitions of care service composed of nurse navigators, pharmacists, and medical providers reduced 30-day hospital readmissions among patients who received all components of the intervention.
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Applying Weighting Methodologies to a Commercial Database to Project US Census Demographic DataThis study tests the feasibility of projecting commercial insurance demographic information to the US Census population, and creating the framework for a simple weighting scheme.
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Cost-effectiveness of Intensification With SGLT2 Inhibitors for Type 2 DiabetesAdding a sodium-glucose co-transporter 2 (SGLT2) inhibitor dominated switching to a glucagon-like peptide 1 receptor agonist over the lifetimes of patients with type 2 diabetes not at glycated hemoglobin A1c target after treatment with metformin plus a dipeptidyl peptidase-4 inhibitor.
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The Influence of Provider Characteristics and Market Forces on Response to Financial IncentivesWe determine a specialist physician phenotype responsive to financial incentives that may be leveraged to identify physicians and markets well-suited for participation in alternative payment models.
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Substitutive Hospital at Home for Older Persons: Effects on CostsSubstitutive Hospital at Home care for 4 common conditions is associated with cost savings.
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The Emerging Business Models and Value Proposition of Mobile Health ClinicsMobile health clinics represent promising vehicles through which high quality, cost-effective care can be delivered to patients, especially in underserved areas.
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Cost-Effectiveness of Pharmacist Postdischarge Follow-Up to Prevent Medication-Related AdmissionsA multivariable sensitivity analysis conducted on a pharmacy follow-up program of high-risk patients demonstrated cost savings to hospitals in 98.3% of head-to-head trials across 1000 hypothetical hospitals.
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Effect of Physician-Specific Pay-for-Performance Incentives in a Large Group PracticeThis study examined the effect of physician-specific pay-for-performance incentives on well-established ambulatory quality measures in a large group practice setting.
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Cost of Pharmacotherapy for Opioid Use Disorders Following Inpatient DetoxificationThe mean 24-week cost per participant was $5416 for extended-release injectable naltrexone (57% detoxification, 37% medication, 6% provider/patient) and $4148 for buprenorphine-naloxone (64% detoxification, 12% medication, 24% provider/patient).
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Breast Cancer Multigene Testing Trends and Impact on Chemotherapy UseA multigene test for breast cancer recurrence risk was used in a minority of eligible patients, yet was associated with a decrease in chemotherapy use.
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Medical Home Transformation and Breast Cancer ScreeningBreast cancer screening may not improve in early medical home implementation.
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Guided Care and the Cost of Complex Healthcare: A Preliminary ReportThe early months of a cluster-randomized trial suggest that Guided Care is associated with a trend toward a net reduction in total healthcare expenditures.
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Patient Factors Associated With Following a Relocated Primary Care Provider Among Older AdultsThere are differences between patients who elect to maintain continuity with their PCP versus those who choose to change their PCP for convenience.
