Authors
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Key Takeaways for the Management of HIV PrEPA panel of experts share closing thoughts and advice for the management and uptake of HIV PrEP therapy.
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Role of Pharmaceuticals in Value-Based Healthcare: A Framework for SuccessA framework for the role of pharmaceuticals in value-based healthcare, practical examples from organizations that have made the transition, and implementation considerations.
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Bridging the Digital Divide: Mobile Access to Personal Health Records Among Patients With DiabetesRacial/ethnic minorities and patients living in poorer neighborhoods were more likely to access their personal health record exclusively with a mobile device.
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Real-World Economic Value of a 21-Gene Assay in Early-Stage Breast CancerUniversal gene expression profiling of patients with stage II breast cancer resulted in outpatient savings of $11,000 (inclusive of testing costs) within 6 months of initiation of medical therapy.
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Enhanced Care Coordination Improves HIV Viral Load Suppression RatesEnhanced care coordination in New York City that leveraged surveillance data with a health plan’s Medicaid managed care roster improved its HIV viral load suppression rate.
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Preferred Roles in Treatment Decision Making Among Patients With Cancer: A Pooled Analysis of Studies Using the Control Preferences ScaleThis pooled analysis assesses preferred roles in treatment decision making, actual roles, and preferred versus actual discordance among 6 studies of patients with cancer.
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LACE+ Index as a Predictor of 90-Day Plastic Surgery OutcomesPatients with higher LACE+ index scores have significantly greater risk of unplanned readmission, emergency department visits, and reoperation after plastic surgery.
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Antibiotic Use for Viral Acute Respiratory Tract Infections Remains CommonAntibiotic use for acute respiratory tract infections that are largely viral remains common. Macrolide use has increased since 2007, and 9% of patients received a second antibiotic within 30 days.
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Implications of Evolving Delivery System Reforms for Prostate Cancer CareHealthcare integration was associated with small declines in treatment, but no change in overtreatment of prostate cancer. Integrated care delivery alone may be insufficient to curtail overtreatment.
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Cost Analysis of COPD Exacerbations and Cardiovascular Events in SUMMITThis cost analysis using data from the Study to Understand Mortality and Morbidity in COPD (SUMMIT) trial found that fluticasone furoate/vilanterol reduced the rates and costs of combined chronic obstructive pulmonary disease (COPD) exacerbations and revascularization/cardiovascular events versus placebo.
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Comparative Effectiveness Research: Challenges for Medical JournalsIn order to encourage dissemination, this commentary is freely available in PLoS Medicine, and will also be published in Medical Decision Making, Croatian Medical Journal, The Cochrane Library, Trials, and Journal of Clinical Epidemiology.
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Development and Implementation of an Academic Cancer Therapy Stewardship ProgramA cancer therapy stewardship program can be used to improve clinical quality and patient care by emphasizing the importance of value and evidence in oncology.
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VA Geriatric Scholars Program’s Impact on Prescribing Potentially Inappropriate MedicationsPrimary care teams reduced their prescribing of potentially inappropriate medications to older veterans after participation in the Veterans Affairs (VA) Geriatric Scholars Program.
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Oral Anticoagulant Discontinuation in Patients With Nonvalvular Atrial FibrillationThe risk of discontinuation of oral anticoagulant therapy (both warfarin and direct oral anticoagulant therapies [DOACs]) among nonvalvular atrial fibrillation patients was high. Although the hazard ratio for discontinuation favors DOACs, it is unlikely that the small difference in discontinuation relative to warfarin is clinically meaningful.
