The AJMC® Migraine compendium is a comprehensive resource for clinical news and expert insights for the recurring type of headache, which is accompanied by side effects.
April 20th 2023
This quantitative and qualitative analysis highlights differences in prior authorization requirements for migraine drugs from nearly 50 managed care organizations and summarizes broad types of criteria used.
Low Doses of CGRP Trigger Female-Specific Migraine Response
April 12th 2019Researchers of a recently published study used preclinical behavioral models of migraine to determine that the application of calcitonin gene-related peptide (CGRP) to the dura mater, or the protective outer layer between the skull and the brain, in mice triggers pain responses only in females.
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Review Reaffirms Beta-Blockers for Migraine Prevention
April 1st 2019A recent literature review assessed the efficacy of beta-blockers to prevent migraine and tension headache. It found that propranolol worked better than placebo for episodic migraine headaches, but the evidence for efficacy in tension headaches was limited.
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Vestibular Migraine Associated With Various Indicators, Comorbidities
March 23rd 2019A recent retrospective, single-center study sought to characterize symptoms associated with vestibular migraine attacks, symptoms in between attacks, psychiatric comorbidities, and interictal neuro-otologic examination findings.
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The Current Landscape of CGRP Inhibitor Coverage
March 19th 2019In the United States, nearly 50 million Americans suffer from migraine, the majority of whom are between 25 to 55 years of age. The costs of treating this large population have been estimated to be $22 billion annually. A new report, published by the Pharmacy Benefit Management Institute, found that direct healthcare costs for patients with migraine were estimated at $2571 higher than those for similar patients who don’t experience migraine.
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Insufficient Evidence for Anti-CGRP Treatment Guideline for Migraine
March 15th 2019The European Headache Federation (EHF) recently sought to create an expert- and evidence-based guideline for the treatment of migraine with monoclonal antibodies that target the calcitonin gene-related peptide (CGRP). However, in reviewing available research, the EHF found that there was not enough evidence to provide a guideline based on the Grading of Recommendation, Assessment, Development, and Evaluation approach.
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Migraine With Visual Aura Associated With Increased Risk of AF
March 2nd 2019In a recent study, researchers looked to analyze the association of migraine that presents with visual aura with atrial fibrillation (AF) as migraines with a visual aura are associated with a cardioembolic stroke risk.
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Psychological Treatment Reduces Headache Frequency, Study Finds
February 23rd 2019A group of researchers systematically reviewed previously published literature about psychological treatment in primary headache and its effectiveness. The results were published in The Journal of Headache and Pain.
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Review Find Moderate Evidence That Aerobic Exercise Lowers Number of Migraine Days
February 16th 2019Researchers have determined that there is moderate quality evidence suggesting that aerobic exercise as prophylactic treatment can decrease the number of migraine days among patients with migraine.
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Researchers Identify Signal Components Associated With Unpleasantness Among Patients With Migraine
February 9th 2019Hoping to clarify the pathogenic mechanism that underlies migraine attacks triggered by sound, researchers have identified specific signal components associated with unpleasantness for patients with migraine.
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American Headache Society Includes CGRP Inhibitors in Updated Consensus Statement
January 15th 2019Providing healthcare professionals with up-to-date guidance for the use of preventive and acute treatments for migraine, the American Headache Society has published a consensus statement outlining indications for initiating, continuing, combining, and switching the treatments.
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