Currently Viewing:
SGO Annual Meeting on Women's Cancer
Dr Martha Gaines Discusses the Importance of the Patient Voice
March 25, 2018
Clinical Trials Can Reduce Disparities in Advanced Ovarian Cancer, but Funding Is Needed, Researchers Say
March 25, 2018
Dr Scott Page: Diversity in Healthcare Improves Patient Outcomes
March 25, 2018
Deciding When to Use PARP Inhibitors, and Which One
March 25, 2018
Boys Don't Get HPV Vaccination Because Doctors Don't Recommend It, Study Finds
March 25, 2018
Currently Reading
Dr Victoria Bae-Jump on Obesity and Endometrial Cancer
March 25, 2018
Putting PARP Inhibitor Perspectives Into Practice in "Beyond the Guidelines" Session
March 26, 2018
Dr Oliver Dorigo on New, Innovative Therapies in Gynecologic Cancers
March 26, 2018
Dr William Cliby Explains Predictors of Patient Outcomes in Ovarian Cancer
March 26, 2018
Study Explores Mechanism Linking Statin to Reduced Tumor Size in Endometrial Cancer
March 26, 2018
Study Models ASCO Alternative Payment Model in Advanced Ovarian Cancer Care
March 27, 2018
Dr Sean C. Dowdy: Reducing Opioid Abuse in Patients Undergoing Surgery for Gynecologic Malignancies
April 04, 2018
Dr Victoria Bae-Jump Discusses Standard of Care, Novel Therapies For Endometrial Cancer
April 11, 2018
Dr Oliver Dorigo: Novel Therapies Being Researched by Stanford for Gynecologic Malignancies
April 13, 2018
Dr Anna Beavis Highlights Importance of Addressing Gender Gaps in HPV Vaccination
April 15, 2018
Dr William Cliby: Patient Factors and Surgery, Quality of Care For Ovarian Cancer
April 16, 2018
Dr Sean C. Dowdy Discusses Improving Surgical Outcomes in Gynecologic Oncology
April 18, 2018
Dr Martha Gaines: Turning Experience as Cancer Survivor into Patient Advocacy
April 20, 2018
Dr Oliver Dorigo on Identified Biomarkers in Gynecologic Malignancies
April 25, 2018
Dr Victoria Bae-Jump on Challenges in Treating Patients With Endometrial Cancer
April 27, 2018
Dr William Cliby Discusses Improving Surgical Outcomes in Ovarian Cancer
April 30, 2018
Dr Sean C. Dowdy on Delays Between Discovering Improved Treatment, Practice and the Application of It
May 05, 2018
Dr Martha Gaines on Helping Patients Understand Their Disease, Identifying Available Resources
May 11, 2018
Dr Oliver Dorigo Discusses an Interdisciplinary Approach to Care in Gynecologic Oncology
May 14, 2018

Dr Victoria Bae-Jump on Obesity and Endometrial Cancer

Approximately 60% of patients with endometrial cancer are obese, explained Victoria Bae-Jump, MD, PhD, associate professor, gynecologic oncology, University of North Carolina Lineberger Comprehensive Cancer Center.


Approximately 60% of patients with endometrial cancer are obese, explained Victoria Bae-Jump, MD, PhD, associate professor, gynecologic oncology, University of North Carolina Lineberger Comprehensive Cancer Center.

Transcript

What impact does obesity have on risk and progression of endometrial cancer?

Endometrial cancer is by far the most obesity-driven cancer. Probably up to 60% or more of endometrial cancer patients are obese according to the numbers, so we know there’s a very strong risk factor for the development of this disease, no question. We also know that it may also be associated with worse outcomes for this disease, although it’s a little bit controversial of whether worse outcomes are related to actually cancer-specific outcomes or just all-cause mortality. But, endometrial cancer patients, given that obesity if such a huge risk factor, have the highest comorbidity of all cancers out there, and they actually more likely to die of cardiovascular disease than their endometrial cancer.

So, there’s no question that obesity is a driver of the development of this disease. I think that obesity status may help us figure out what metabolic treatments may be important in treating this disease, but I think right now we don’t treat obese and lean patients any different. But, there is some research going on; I think in my lab we’re trying to see if there are any targeted agents that be more helpful in cancers that arise in the setting of obesity, but I think that right now the data is still young, and so we just have to keep continuing to look at it and continue to work on it.

The 1 thing though to remember is that when this cancer is diagnosed in obese patients, it’s also a great teaching moment to encourage them for better eating patterns and exercise and all these things, irregardless of cancer outcomes, this is a good teaching moment to get them to improve their overall health.

 
Copyright AJMC 2006-2019 Clinical Care Targeted Communications Group, LLC. All Rights Reserved.
x
Welcome the the new and improved AJMC.com, the premier managed market network. Tell us about yourself so that we can serve you better.
Sign Up