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The FDA granted accelerated approval to Immunomedics’ Trodelvy (sacituzumab govitecan-hziy) as the first antibody-drug conjugate that targets the Trop-2 antigen. Trodelvy is indicated for treatment of relapsed or refractory metastatic triple-negative breast cancer (TNBC) that has spread to other parts of the body.

Researchers found that signs of autoimmunity can appear in Parkinson disease years before an official diagnosis, which may allow for heightened detection before symptom onset and greater preventive measures to slow disease progression.

Some rural communities are only now seeing an uptick in coronavirus disease 2019 cases; lifesaving organ donations have seen precipitous drops as of late; the current social distancing measure of 6 feet may not apply in all cases.

As some states move to eschew social distancing recommendations by beginning plans to reopen businesses amid the coronavirus disease 2019 pandemic, a group of economists highlight in a recent study that the potential benefits of social distancing in saving lives far outweigh the projected damage to the economy.

Individuals with type 2 diabetes (T2D) who underwent Roux-en-Y gastric bypass exhibited greater weight loss, a slightly higher T2D remission rate, less T2D relapse, and better long-term glycemic control compared with those who had sleeve gastrectomy, according to a study published in JAMA Surgery.

Visual impairment may be a risk factor for dementia, according to a study published in JAMA Ophthalmology in which researchers compared the likelihood of incident dementia or mild cognitive impairment among women with and without baseline visual impairment.

Cognitive impairment is a well-documented adverse effect of treatment from breast cancer. Complications from it can appear soon after treatment has begun or far down the road.

Nearly 5 in 10 individuals in the United States—150 million Americans—live where pollution levels are often too dangerous to breathe, according to the American Lung Association’s annual State of the Air Report, released today. Poor air quality has been linked to higher rates of chronic diseases, comorbidities, and poor health outcomes. Several studies suggest poor air quality is a contributing factor to the prevalence of coronavirus disease 2019 (COVID-10) in some communities.

CMS will allow clinicians who participate in the Quality Payment Program to earn credit in the Merit-based Incentive Payment System (MIPS) for participation in a coronavirus disease 2019 (COVID-19) clinical trial and reporting clinical information; President Trump announced via Twitter that he would sign an executive order to temporarily suspend immigration; findings from antibody testing in Los Angeles indicate that more people have been infected with COVID-19 than initially confirmed.

Structural volume and connectivity changes of the cerebellum may impact headache persistence in patients with high-frequency migraine (HFM), according to a study published in The Journal of Headache and Pain.

Nearly 7 in 10 employees indicated in a survey by mental health provider Ginger that the coronavirus disease 2019 (COVID-19) pandemic is the most stressful time of their entire professional career, which has aligned with stark increases in new prescriptions of antidepressant, antianxiety, and anti-insomnia medications.

Chlamydia, gonorrhea, syphilis, and trichomoniasis are 4 sexually transmitted infections (STI) that have seen sharp increases in occurrence over the past 10 years. Their combined overall rate rose 31% between 2013 and 2017 and correlate with a lower overall HIV testing rate among adolescents.

The FDA Friday approved pemigatinib for adults with previously treated, unresectable locally advanced or metastatic cholangiocarcinoma with a fibroblast growth factor receptor 2 (FGFR2) fusion or other rearrangement.

Which pulmonary manifestations were present among patients with connective tissue disorder?

Patients with obstructive sleep apnea–hypopnea syndrome (OSAHS) had significantly higher Alzheimer disease biomarkers in their plasma than those without the condition, which may explain the occurrence of cognitive decline in these populations, according to study findings.

Obesity increases the risk of developing type 2 diabetes (T2D) regardless of genetic predisposition to the disease, according to a study published in Diabetologia. These findings emphasize that having a normal body weight is crucial to prevent T2D.

In the eligibility terms and conditions published by HHS for practices seeking emergency funding, surprise medical billing is banned for patients with the coronavirus disease 2019 (COVID-19); more Americans are worried the United States will lift restrictions on the pandemic too soon than they are about the economic shutdown; nursing homes are now required to report cases of COVID-19 to the CDC.

As more patients with heart disease live longer, physicians need better tools to assess frailty in those with heart failure. New study results suggest a multidimensional assessment approach is preferable to one that focuses only on physical metrics.

Researchers found that the factors most associated with health related quality of life (HRQOL) in patients with facial palsy are age, bilateral facial palsy, severity of facial palsy, anxiety, and key personality traits, including extraversion and emotional stability.

Despite experiencing general fears, patients with rare diseases may be the most equipped to handle the coronavirus disease 2019 (COVID-19) pandemic, according to some experts.

Psoriasis typically emerges among the young, while Alzheimer disease is mainly a disorder of old age, raising the question of whether psoriasis has an impact on the later development of neurodegenerative diseases.

Difficulty swallowing affects about one-third of patients with multiple sclerosis.

AHIP wants the FDA and FTC to streamline product approvals, clarify the regulations governing biosimilars, put a stop to attempts to discourage people from using biosimilars, and start educating providers and patients about the safety and efficacy of these products.

There is a greater risk of hormone receptor–positive breast cancer if a patient is obese. Researchers from the University of Louisville have discovered a possible new link between obesity and a greater risk for developing breast cancer: adipose fatty acid binding protein.

Despite positive results seen from the use of chloroquine and hydroxychloroquine in some patients hospitalized with coronavirus disease 2019 (COVID-19), concern is mounting about how these drugs affect patients’ cardiovascular health, specifically the heart.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

President Donald Trump yesterday released broad guidelines to drive a re-opening of the US economy in the wake of the coronavirus disease 2019 (COVID-19) pandemic, outlining conditions that should be in place while leaving final decisions to the nation’s governors.

Despite being at an increased risk for HIV and hepatitis C, persons who inject drugs (PWID) are tested at dismal rates for both: just 8.6% and 7.7%, respectively, according to data from 2010 to 2017. PWID who live in rural communities are more likely to face barriers to adequate testing and care for both diseases.

This week, the top managed care news included a report that accountable care organizations may drop out of the Medicare Shared Savings Program; states and healthcare plans address unemployment brought on by COVID-19; a sneak peek of the virtual 2020 Community Oncology Conference.

Manufacturers are reporting shortages of a common medication for sexually transmitted disease (STDs); rates of cancers related to human papillomavirus (HPV) increased from 2007 to 2016; early trial data show patients infected with coronavirus disease 2019 (COVID-19) respond to remdesivir.