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A retrospective, exploratory analysis identifies biomarkers predictive of spinal muscular atrophy (SMA) response to nusinersen and suggests the efficacy of using machine learning algorithms to anticipate patient outcomes.

The Center on Health Equity and Access spotlights the latest health equity news, research, and initiatives to reduce health care disparities and improve access to care.

This research highlights the close relationship between pollen-induced allergic rhinitis, sensitization, and asthma.

In a recent study, reducing dietary sodium demonstrated a blood pressure–reducing effect similar to that of a commonly used first-line antihypertensive medication.

Postmenopausal women experienced more severe effects, with a 20.1% increase in insulin resistance, according to the findings.

Governor Kathy Hochul proposed this week that New York become the first state to require health systems to implement cyber defenses; a new report from the World Health Organization and the CDC highlighted a staggering rise in measles cases and deaths in 2022; a study published this week claimed that more than a tenth of fecal immunochemical tests used for routine colorectal cancer screening could not be processed by labs.

Plasma ceramides and sphingomyelins with palmitic acid were linked to a 34% and 37% increased risk of sudden cardiac death (SCD) per higher SD of log sphingolipid levels, respectively.

A Biologics License Application has been submitted to the FDA review for sotatercept in the treatment of pulmonary arterial hypertension.

The use of olaparib as a monotherapy or in combination with cediranib did not provide a statistically significance overall survival (OS) benefit compared with standard of care platinum-based chemotherapy in patients with recurrent, platinum-sensitive ovarian cancer.

The study findings provide the first in-depth look at the relationship between chromosomal changes in tumor cells and immune components of the tumor microenvironment.

A phase 3 trial in symptomatic and anemic patients with myelofibrosis (MF) met its primary end point, seeing a significant symptom reduction at 24 weeks with momelotinib vs danazol.

The FDA approved delandistrogene moxeparvovec-rokl (Elevidys, Sarepta Therapeutics) in June to treat Duchenne muscular dystrophy in ambulatory pediatric patients aged 4 through 5 who have a confirmed DMD gene mutation.

More than 77,000 additional doses of nirsevimab-alip will be distributed for respiratory syndactyl virus (RSV) immunization in infants.

The FDA has approved pembrolizumab (Keytruda) in combination with fluoropyrimidine- and platinum-containing chemotherapy for the first-line treatment of adult patients with locally advanced unresectable or metastatic, HER2-negative gastric or gastroesophageal junction adenocarcinoma.

The reported neurofilament light elevation preceding confirmed disability worsening events highlighted the value of NfL as an early biomarker of disability worsening and points to the existence of different windows of dynamic central nervous system pathology.

The tool assesses the risk of heart attack, stroke, and, for the first time, heart failure, offering a more comprehensive perspective on cardiovascular health.

Repotrectinib achieved a high objective response rate and durable response in the pivotal TRIDENT-1 trial.

The CDC has published updated recommendations for the postexposure prevention and treatment of Bacillus anthracis (anthrax) infection; the FDA has granted marketing approval to an at-home chlamydia and gonorrhea test; lawmakers and Veterans Affairs officials acknowledge the potential for psychedelic drugs to treat veterans’ mental health conditions and prevent suicide.

According to researchers, the most prevalent risk factors in children with type 1 spinal muscular atrophy (SMA) are hypercalciuria and elevated urine specific gravity.

Investigators note that prospective research is needed to confirm the efficacy of vitamin D supplements in preventing chemotherapy-induced peripheral neuropathy in patients with breast cancer.

With improved survival becoming more common among individuals who have Duchenne muscular dystrophy (DMD), cardiomyopathy is also increasing in prevalence among this population.

Although telehealth is broadly accepted as a mode of cancer rehabilitation, accessibility and in-person challenges exist.

Remibrutinib, an investigational, highly selective Bruton tyrosine kinase inhibitor, showed favorable results in the treatment of chronic spontaneous urticaria (CSU) in as early as 2 weeks in the phase 3 REMIX-1 and REMIX-2 studies.

Male adolescent and young adult patients were found to have an increased risk of keratoconus if they had attention-deficit/hyperactivity disorder (ADHD), regardless of confounders.

Patients with chronic obstructive pulmonary disease (COPD) who were from minority ethnic backgrounds were found to have lower adherence to treatment interventions compared with the general population.

New research highlighted how aspirin is unnecessary in antithrombotic regimens for patients with advanced heart failure and fully magnetically levitated left ventricular assist devices (LVADs).

A class action lawsuit was filed against UnitedHealth Group and a subsidiary for allegedly using an algorithm to deny rehabilitation coverage for seriously ill patients; US and China officials are finalizing an agreement to crack down on fentanyl; a study published Tuesday projected global heat deaths to increase by 370% if no action is taken against global warming.

Patients who have HIV and are using antiretroviral therapy (ART) did not have adverse outcomes when using nivolumab for cancer treatment.