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Chronic obstructive pulmonary disease (COPD) is associated with shorter survival and marked differences in early stages of non-small cell lung cancer (NSCLC).

Researchers in Australia studying thunderstorm-triggered asthma suggested that ways to better stratify at-risk individuals are needed.

FDA approved alpelisib (Piqray), an oral drug to be used in combination with endocrine therapy fulvestrant for the treatment of men and postmenopausal women with hormone receptor (HR-positive), human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer following disease progression on or after an endocrine-based regimen.

The FDA approved ruxolitinib (Jakafi) for another indication, this time for the treatment of steroid-refractory acute graft-versus-host disease in adult and pediatric patients 12 years and older.

A study has found that 28% of men and 26% of women between the ages of 35 and 50 years have osteopenia and are at risk for osteoporosis.

The FDA approved a smartphone-controlled medical device that claims to treat migraine.

A federal judge has blocked a Mississippi law that would ban abortions 6 weeks into pregnancy; Teva Pharmaceuticals settled with state of Oklahoma for $85 million 2 days before opioid trials were set to begin; the governor of Maine has signed a bill that will remove nonmedical exemptions for vaccinations.

The analysis showed the opioid cessation rate at 18 months after surgery was 64% among those who used the pain medication before joint replacement, and 95% among those who did not.

Analysis of findings from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study found no association between sickle cell trait and cognitive impairment.

A study combining ruxolitinib and buparlisib in myelofibrosis showed only a modest benefit compared with ruxolitinib alone, and further studies to see if there is a synergistic effect between the 2 agents will not continue.

Spanish researchers have identified 3 biomarkers, including minimal residual disease negativity, that can help define those elderly patients with multiple myeloma (MM) who are likely to achieve long-term disease control.

Higher migraine-related costs were the top indicators of a patient having chronic migraine, according to a poster presented at ISPOR 2019.

AveXis—a Novartis company—announced that it will work with payers to implement 5-year outcomes-based agreements and novel pay-over-time options. The company also said it will offer a patient program to support affordability and access.

By 2060, an estimated 48 million people each year will die with serious health-related suffering, representing an 87% increase from 2016.

A study has identified links between osteoporosis and hypertension, coronary heart disease, and cerebral infarction.

Evobrutinib, an oral Bruton’s tyrosine kinase inhibitor, reduced gadolinium-enhancing lesions in patients with multiple sclerosis.

https://www.pharmacytimes.org/on-demand/exploring-therapeutic-targets-of-the-beta-amyloid-pathway-to-slow-the-progression-of-alzheimer-disease

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

This week, the American Psychiatric Association released results of a public opinion survey on several key mental health issues, including how well employees can access mental health care at work.

A bipartisan group of senators has revealed healthcare legislation that would address surprise medical bills and add transparency to the rebate system; starting in January, Colorado will cap insulin prices at $100 per month; the FDA has authorized marketing of the first diagnostic test for Zika virus.

This week, the top managed care news included a study questioning the Hospital Readmissions Reduction Program; FDA issuing a warning about do-it-yourself artificial pancreas systems; measles cases reach the highest level since 1994.

After a rural syringe service program was indefinitely suspended, individuals who inject drugs had a greater risk of contracting HIV and hepatitus C virus.

A new Commonwealth Fund report details the effects of high premium contributions and out-of-pocket spending relative to income for households with employer-based health insurance.

New research has identified how bone cells subdue cancer cells that have reached the bone so that the cancer cells remain dormant for decades. The finding may help researchers develop new treatments to prevent or treat metastatic disease and put cancer cells to sleep permanently.

A well-known brand of blood glucose meters, lancets, and test strips has tapped Sanvita Medical to develop sensors that integrate with its OneTouch Reveal diabetes management app.

As a precursor to myeloma, smoldering multiple myeloma (MM) currently has no treatment. In fact, the standard of care is observation until the patient starts to present with symptoms. However, according to new research that will be presented at the American Society of Clinical Oncology’s annual meeting in Chicago, Illinois, held May 31 to June 4, early treatment of smoldering MM may delay progression to full-blown disease.

Senator Kamala Harris, D-California, has reintroduced a bill to address racial disparities in maternal healthcare; a study found that egg consumption is not linked to a higher risk of stroke; cannabidiol has the potential to treat cravings for heroin and other opioids.