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The scientists used machine learning to test the algorithm and believe it could double the number of women who would be treated with poly (ADP-ribose) polymerase (PARP) inhibitors for breast cancer.

Incidence of nonvertebral fractures significantly decreased as T-scores improved during treatment with denosumab for osteoporosis.

The investment fund spun off from the Multiple Myeloma Research Foundation will start at $50 million and will be self-sustaining, focusing on early-stage biotech companies.

Researchers recently found a 2-way association between onset of fibromyalgia (FM) and that of migraine in patients with migraine and those with FM, respectively.

Health centers in Medicaid expansion states are more likely to report improvements in financial stability, offer medication-assisted treatment for opioid addiction, and coordinate care with social service providers in the community compared with health centers in nonexpansion states.

The FDA creates an advisory list for dietary supplements; researchers in Israel bio-printed a small-scale heart with human tissue and blood vessels; patient advocates lobby to lift a ban on a controversial fertility treatment.

While digital health companies strive to address important healthcare issues by developing products and service offerings in various categories such as genome sequencing, analytics, telemedicine, mobile apps, and population health management tools, little evidence is available in the digital space when it comes to peer-reviewed publications, measurement of potential impact, and effect on patients with the greatest burden of disease, says Meridith Peratikos, Director of Enterprise Research, axialHealthcare.

Among veterans admitted to the hospital for chronic obstructive pulmonary disease (COPD) exacerbation, women were evaluated and treated differently than men prior to hospitalization and had better hospital-associated outcomes.

Among patients with multiple myeloma treated with older proteasome inhibitors, those who developed peripheral neuropathy (PN) had significantly higher costs, suggesting that newer therapies may maintain effective treatment while lowering the economic and disease burden of PN in these patients.

Results of the landmark study, the first in a series of renal outcomes studies for SGLT2 inhibitors, will be of great interest to policy makers given the cost of dialysis to Medicare.

For endocrinologists, a cardiologist, a diabetes educator, and a room full of fellow health workers, the cost of doing nothing—not just to treat diabetes, but also to prevent it— is what feeds into the exorbitant cost of the disease, according to presentations and a panel at the inaugural meeting of the Institute for Value Based Medicine (IVBM) in Diabetes, an initiative of The American Journal of Managed Care®.

Prevalence of depressive symptoms among individuals with HIV may lead to an increased risk of mortality.

A preliminary study discussed how a vaccine regimen stimulated dendritic cells to attack tumors, which could point to a new way of making immunotherapy effective in cancers that have proved resistant to treatment thus far.

During the European Congress of Clinical Microbiology & Infectious Disease (ECCMID), being held in Amsterdam, the Netherlands, April 13-16, researchers are presenting findings that suggests the mode of delivery influences the development of gut microbiota in infants, regardless of a mother’s use of antibiotics, which could then affect infants’ respiratory health during his or her first year.

It's been about a year since the FDA approved the first in a new type of drug to prevent migraines. Here are 5 ways migraines impact patients, from workplace issues to other related health conditions.

Study data revealed that 55% of women over age 70 are at risk of fragility fractures, but 75% of these women are not treated for osteoporosis.

Results from a recent study suggest that a revolutionary treatment may have the potential to slow, stop, or even reverse the progression of Parkinson disease.

The FDA has granted accelerated approval to erdafitinib (Balversa) for the treatment of adult patients with locally advanced or metastatic bladder cancer with fibroblast growth factor receptor (FGFR)3 or FGFR2 mutations who have progressed on platinum-containing chemotherapy.

Approximately 45% of cancer deaths expected in 2019 will be related to modofiable risk factors, such as smoking and alcohol use. However, the prevalence of these risk factors vary by racial/ethnic group, as well as education level.

This week, the top managed care news included CDC clarifying its opioid guidelines for chronic pain; pharmacy benefit managers testifying before a Senate committee; Sanofi expanding its insulin savings program starting in June.

When antibiotics were discovered, they were considered a miracle. Decades of overuse have created a current public health crisis with a growing number of antibiotic-resistant bacteria. However, not all hope is lost in the fight against antibiotic resistance. There are programs in place to promote judicious use of antibiotics and policies and funding to help incentivize development of new antibiotics.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

Women who are screened for cervical cancer are significantly less likely to develop rare types of the cancer, especially among women who had 2 tests.

Human papillomavirus (HPV) infection rates are increasing among women under age 40 who haven't received the HPV vaccination; Ride Aid will stop the sale of e-cigarettes over the next 90 days; the Ohio governor signed a ban on abortion after a detectable heartbeat with no exceptions for pregancies resulting from rape or incest.

A recently published study looked to evaluate the effect of a single dose of nilotinib (Tasigna) in patients with PD. While nilotinib is FDA approved for the treatment of adult patients with chronic myeloid leukemia and not PD, the drug is able to penetrate the blood-brain barrier and reduce inflammation as well as lower levels of a toxic protein that prevents the brain from utilizing dopamine stored in vessels in areas of the brain that may control movement.

Researchers of a recently published study used preclinical behavioral models of migraine to determine that the application of calcitonin gene-related peptide (CGRP) to the dura mater, or the protective outer layer between the skull and the brain, in mice triggers pain responses only in females.

The filing comes as recent upgrades to NCCN guidelines expand the role of testing in the treatment of ovarian cancer.

In a disucssion about closing the rural cancer care gap, 3 themes emerged: local efforts, clinical trial access, and telehealth.