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The genetic determinants of sleep and migraine partly overlap, suggesting sleep disturbances may causally influence migraine etiology and could be targets for migraine treatment, according to results of a Mendelian randomization study.

The FDA will move rapidly to clear Pfizer's and Moderna’s coronavirus disease 2019 vaccines for emergency use; approval of Alkermes' ALKS 3831 is pending; California's governor is tightening restrictions for 94% of the state’s residents.

Expansion of insurance coverage due to the Affordable Care Act led to a reduction in the use of emergency services for patients with asthma in New York City.

Supplemental screening for breast cancer, beyond the standard-of-care mammography, may benefit some women who have dense breast tissue.

Artificial intelligence (AI) frees up time for clinicians, noted Anthony L. Loschner, MD, assistant professor and associate program director, Critical Care Fellowship Program, Virginia Tech Carilion School of Medicine.

Finerenone may represent an important step forward to reducing cardiac illness and death in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), the study said.

A machine learning approach that works to identify mitochondrial impairments, a potential mechanism underlying the pathogenesis of Parkinson disease (PD), accurately distinguished between patients with PD and healthy controls.

Half of patients with type 2 diabetes (T2D) exhibit very high cardiovascular risk while the majority are at a high risk of fatal heart attack or stroke, according to new research published in the European Journal of Preventive Cardiology.

An abnormal red reflex finding most likely reflects an underlying ocular pathology in infants, but finding a normal red reflex during screening does not altogether exclude ocular disease.

Although half of US rheumatologists have patients for which nonmedical switching has been suggested, only 35% were likely to switch patients with rheumatoid arthritis doing well on a reference product to a biosimilar.

Even heterosexual women are at risk of contracting HIV, so gay men should not be singled out as the only population with a transmission risk, said Milena Murray, PharmD, MSc, BCIDP, AAHIVP, associate professor, Midwestern University College of Pharmacy.

The investigator of the STRENGTH study says findings raise questions about the landmark REDUCE-IT trial, but other evidence suggests the drugs involved are different.

A loosening of Missouri’s permit-to-purchase and concealed carry firearm laws may have contributed to increased rates of firearm suicides among young residents, according to a recent study published in JAMA Network Open.

As some private health insurance companies move to end waivers of cost sharing for virtual care, there will be several aspects to monitor for employers, particularly its impact on accessibility and potential deferral of health care services.

Dupilumab, with or without topical corticosteroids, significantly reduced pain and discomfort in patients with moderate to severe atopic dermatitis.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

For patients with polycythemia vera (PV), there are no differences in recommendations for preventing complications when using ruxolitinib than for myelofibrosis (MF).

A study looking at chronic obstructive pulmonary disease (COPD) and coronary heart disease found that inhaled corticosteroids (ICS) reduced future cardiac events in patients not known to have coronary heart disease.

Lowering the higher rates of diabetes seen among racial and ethnic minorities requires solutions to address all of the major factors that contribute to diabetes prevalence.

A multidisciplinary spine intervention can reduce chronic back pain–related health care utilization and costs, according to a study published in Spine.

A registry study suggests 4 in 5 patients with heart failure might benefit from the SGLT2 inhibitor dapagliflozin.

Patients with Parkinson disease (PD) who do not experience tremor were found to show improvements in reward learning after taking dopaminergic medication, while those with PD and tremor exhibited no benefit in reinforcement learning.

Findings from the GALACTIC-HF trial presented at AHA Scientific Sessions 2020 showed that patients with heart failure (HF) with reduced ejection fraction who took omecamtiv mecarbil showed a significant 8% relative risk reduction in a composite of a HF event or death from cardiovascular causes, compared with those taking placebo.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

A look into the US cities hardest hit by cases of coronavirus disease 2019 (COVID-19); Anthony Fauci, MD, urges Americans to double down on health precautions amid COVID-19 surges; a study spotlights risk of high health care costs among the insured.

This week, the top managed care news included the Supreme Court signaling willingness to uphold the Affordable Care Act; Pfizer’s coronavirus disease 2019 vaccine shows 90% efficacy; racial disparities in lung cancer screenings and prescribing biologics.

Age, sex, and body mass index typically drive the development of obstructive sleep apnea, noted Krishna M. Sundar, MD, clinical professor, Pulmonary Division, Department of Medicine, medical director, Sleep-Wake Center, University of Utah.

Chimeric antigen receptor (CAR) T cells can be highly effective, but the durability of the therapy has been lacking in many patients with hematological malignancies. Many efforts are underway to fix this problem.