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Researchers have used positron emission tomography scans to identify which patients with a type of human epidermal growth factor receptor 2–positive breast cancer might benefit most from targeted agents alone and can be spared chemotherapy.

Despite the finding that a phase 3 trial of an epicutaneous immunotherapy therapy for peanut allergy did not achieve the lower end of an efficacy end point, it may still represent a viable option for children with peanut allergy, considering the unpredictability of these severe and sometimes fatal reactions.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

Pharmacy benefit managers (PBMs) took $123.5 million in spread pricing from Kentucky Medicaid plans, according to a state report; Richard Sackler, MD, the former president of OxyContin maker Purdue Pharma, repeatedly gave testimony in an opioid lawsuit that conflicts with a federal report, according to court papers; rural state lawmakers in Kansas are pushing a plan to allow the Farm Bureau to offer health insurance coverage, but Democrats and others are critical of the idea.

Employers are placing an increased focus on healthcare benefits and integrating or expanding healthcare offerings. With healthcare costs rising, employers are focusing not only on health plans but also on ways to improve employee experience with healthcare.

This week, the top managed care news included CMS' proposal to cover chimeric antigen receptor T-cell therapy; a study faulting the FDA’s handling of fentanyl oversight; and breast surgeons calling for genetic testing for all patients with breast cancer.

Initial results of a study have found that white blood cell counts and absolute neutrophil counts, which are well-established predictors of risk of infections or febrile neutropenia, can be accurately measured with a finger stick drop of blood and point-of-care hematology results.

The Affordable Care Act (ACA) was associated with expanded insurance coverage and improvements in access to care for women of reproductive age, particularly for those with lower incomes.

Researchers examined the medical costs for patients with a rare subset of chronic obstructive pulmonary disease (COPD) caused by a deficiency in alpha-1 antitrypsin receiving augmentation therapy.

More than one-third of the therapies the FDA approved in the last 2 years includes information on the label identifying patients would benefit the most or experience fewer side effects, found a recently published report from the Personalized Medicine Coalition.

Digital tools for managing diabetes and insulin have proliferated in recent years.

National health spending will climb to 19.4% of gross domestic product in 2027, reaching $6 trillion, according to annual CMS estimates, with growth continued to be boosted by a greying population aging into Medicare.

Patients of all ages see benefits with once-weekly carfilzomib compared with a twice-weekly dose, according to an analysis of the phase 3 A.R.R.O.W. trial.

The FDA is warning against services offering to inject older adults with younger people's blood plasma; Gilead is being accused of providing kickbacks to providers to boost sales of its drugs; and a bill in Maryland would allow minors to consent to preventive treatment for HIV.

Due to continued uncertainty around how aggressively to treat early multiple sclerosis (MS), a group of researchers recently analyzed long-term outcomes in a population-based cohort according to initial treatment strategy.

The majority of countries could see an end to cervical cancer as a public health problem by 2060, according to a new study in The Lancet Oncology.

Unsatisfied with the status quo, younger patients are even more likely to use nontraditional health services, such as walk-in clinics and telehealth, compared with older generations.

Births in freestanding birth centers are increasing, and the number of birth centers is increasing, as well, but capacity is not keeping up with demand. Freestanding birth centers provide many of the same services that are provided for low-risk pregnancies in hospitals, and there is evidence of equivalent or better outcomes of care both here in the United States and in abroad. Yet, freestanding birth centers are paid less than hospitals for doing the same work.

Research comparing outcomes, resource utilization, and costs of multiple sclerosis (MS) found that patients with the disease face substantial burdens that differ among Japan, 5 European Union countries, and the United States.

Researchers have found that multiday corticosteroid administration during chemotherapy delays the diagnosis of and antimicrobial administration for febrile neutropenia.

An FDA program to prevent the inappropriate use of immediate-release fentanyl did not meet its goals of preventing off-label use or to patients who were not already using opioids, a JAMA study reported Tuesday.

Kaiser Permanente will waive annual tuition for the first 5 classes of its new medical school, following a similar move by the New York University School of Medicine; menopause is typically thought of in terms of the end of fertility, but more attention is being paid to the effects of the lack of estrogen on the brain; a federal judge has ordered the US Air Force to temporarily stop discharging service members who are HIV-positive.

Researchers have found the duration and frequency of migraine are associated with these disorders.

The update follows a study published in November that found almost no difference in the frequency of mutations between patients with breast cancer who met National Comprehensive Cancer Network guidelines and those who didn't.

Nonsteroidal anti-inflammatories (NSAIDs) have passed opioids as the most common drug group prescribed to injured workers in California, while payment data show that both dermatological medications and anticonvulsants now rank ahead of opioids in terms of total reimbursements, according to a report examining trends between 2009 and 2018.

As survival rates for people living with HIV continue to increase and the population grows older, cognitive impairment is becoming more common.

While diet soft drinks may seem like a healthier option, the effects of the drinks given the amount of artificial sugar and flavorings haven’t yet been fully studied. Researchers recently sought to evaluate the association between self-reported consumption of artificially sweetened beverages (ASBs) with stroke and its subtypes, coronary heart disease, and all-cause mortality in postmenopausal US women.