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Costs remain the top concern of healthcare purchasers of pharmacy benefits, but employers are also concerned with ensuring appropriate use of medication and adherence to medication, according to a new report from the Pharmacy Benefit Management Institute (PBMI).

Researchers found use of e-cigarettes was nearly twice as effective as nicotine-replacement therapy to help individuals quit smoking, according to a new study in New England Journal of Medicine.

“Medicare for Al” refers to a bill originally introduced to Congress in September 2017 by Senator Bernie Sanders, I-Vermont, with 16 Democratic cosponsors that would create a single, federal, government-administered program to provide healthcare to all US residents. In February 2019, Representative Pramila Jayapal, D-Washington, introduced the Medicare for All Act of 2019, with 106 cosponsors. This bill builds upon the legislation that Sanders introduced, with a few key differences. Here are 5 things to know about the bills.

This week, the top managed care news included Scott Gottlieb, MD, resigning as FDA commissioner; Eli Lilly offering a discounted version of Humalog; and a second patient reported cured of HIV.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

CMS is requesting comment on eliminating regulatory and other barriers that may be impeding interstate health insurance; a study has found a link between secondhand smoke exposure and chronic kidney disease; House Democrats have renewed their push for gun violence research.

While use of palliative care at the end of life has increased, disparities remain, and not all patients who are terminally ill with blood cancers are having discussions about their goals of care at the end of life.

According to a recent study, people with migraines may have altered connections between the somatosensory cortex and the frontal lobe compared with people who do not experience migraines.

IVI seeks comment on its new NSCLC model through April 1, 2019.

The study illuminates how the weight loss, reduction in fatty liver disease, and a decreased risk for cardiovascular disease happens in patients taking SGLT2 inhibitors.

Earlier this week, the FDA granted priority review to a new drug application for fedratinib for the treatment of myelofibrosis. The drug had previously been awarded an orphan drug designation for the treatment of primary and secondary myelofibrosis.

This is part 1 of a 3-part vaccine series covering the potential of vaccines for infectious diseases, the impact of the antivaccination movement, and the promise of vaccines for cancer treatment.

Even moderate drinkers, who consume 7 to 13 alcoholic beverages per week, are at risk for developing high blood pressure, which can lead to heart attack or stoke, according to an abstract to be presented at the upcoming American College of Cardiology Scientific Sessions and Exposition in New Orleans, Louisiana.

Not having enough tissue is often a problem in precision medicine. The senior author of a new study said a liquid biopsy could become a new standard.

Patients with migraine headaches may have a risk of also having dry eye disease (DED).

Planned Parenthood and the American Medical Association have become the latest groups to sue the Trump administration over rule changes to Title X; an Ohio teen testified before a Senate committee about why he defied his mom and get vaccinated; and a federal judge has ruled that a unit of UnitedHealth Group had implemented policies discriminating against patients with mental health and substance abuse disorders.

Those who use e-cigarettes face higher risks of having a heart attack, experiencing emotional distress, and developing coronary artery disease compared to non-users, according to an abstract to be presented at the upcoming American College of Cardiology Scientific Sessions and Exposition in New Orleans, Louisiana.

The FDA is anticipated to release a finalized guidance document any day now around the regulation of fecal microbiota transplants for the treatment of Clostridium difficile infection. The outcome will dictate how they’re priced, who oversees their use, and who can make money off the treatment.

The name of the healthcare offspring of Amazon, Berkshire Hathaway, and JPMorgan Chase is finally here.

Analysis of a 2-year study showed that fluctuations in yearly chronic obstructive pulmonary disease (COPD) exacerbation rates may be associated with variations in Haemophilus influenzae colonization.

The FDA has approved esketamine for adult patients with treatment-resistant depression. The treatment has demonstrated improvement in depression symptoms, as well as sustained improvement in symptoms.

The Trump administration is working on a payment model that would favor home dialysis over in-clinic treatment for kidney disease; California is suing the Trump administration over rule changes to Title X; Trump has ordered the creation of a task force to address veteran suicide.

An analysis of exchange premiums finds that older adults with incomes just above the premium subsidy cutoff (400% of poverty), particularly in rural areas where premiums are highest, have the most severe affordability challenges.

Compared with other drug regimens, a carfilzomib-based regimen resulted in longer time to next treatment, as well as longer overall survival and improved 24-month survival, among patients with relapsed or refractory multiple myeloma (RRMM).

FDA Commissioner Scott Gottlieb, MD, will resign his post in about a month. The physician has been active in fighting youth e-cigarette use, encouraging generic drug competition, and in modernizing approval processes while leading the FDA. Reports said he wants to spend more time with his family.

A second patient has been reported to have been cured of infection with HIV since the start of the epidemic; thousands have reported complications to the FDA with medical devices and implants; a 30-person national ethics committee has been appointed in China to oversee high-risk clinical trials.

Researchers discovered a strong correlation between cerebral small vessel diseases and motor symptoms in patients with Parkinson disease, according to a recent cross-sectional study.

The results come after the American Diabetes Association and the American College of Cardiology have recently issued guidelines calling for the use of GLP-1 receptor agonists for patients with type 2 diabetes and cardiovascular risk.