Currently Viewing:
Newsroom
Currently Reading
Payers Have Room for Improvement in Delivering Pain Care, Study Says
June 22, 2018 – Allison Inserro
5 Things to Know About the CREATES Act
June 22, 2018 – Kelly Davio
AJMC® in the Press, June 22, 2018
June 22, 2018 – AJMC Staff
What We're Reading: Health Agencies Could Change; Pandemic Gaps Highlighted; Cigna Seeks to Cut Overdoses
June 22, 2018 – AJMC Staff
Study Compares Cannabis Benefits for Patients With Chronic Pain and Migraine
June 22, 2018 – Alison Rodriguez
Patients With Myelofibrosis Treated With JAK1/2 Inhibitors at Increased Risk of Lymphomas
June 22, 2018 – Laura Joszt
Neurofilament Light Prevalence Predicts Disease Progression in RRMS
June 21, 2018 – Samantha DiGrande
Tracking Medicaid Expansion
June 21, 2018 – AJMC Staff
FDA Warns Efficacy Concerns in Some Patients Taking Keytruda, Tecentriq
June 21, 2018 – Samantha DiGrande

High Fat Diet Reduces Gut Bacteria and Fights Against Crohn's Disease

Alison Rodriguez
New research suggests that a high fat diet could reduce the bacteria of the gut and, therefore, fight against the harmful inflammation that Crohn’s disease patients experience.
New research suggests that a high fat diet could reduce the bacteria of the gut and, therefore, fight against the harmful inflammation that Crohn’s disease patients experience.

In Case Western Reserve University School of Medicine’s study, the researchers observed a significant decrease in bacterial diversity in mice with Crohn’s-like disease when they were on a plant diet with “good” fats like coconut oil and cocoa butter. The study found that mice on the “good” fat diet had up to 30% fewer types of bacteria in the gut when compared to those fed their normal diet.

There was an apparent different microbial composition between those with the beneficial fat diet and those without. Some of the changes in the mice were found in the feces, while others were apparent in the cecum. Regardless of observation location, the study witnessed a decrease of severe intestine inflammation in mice fed even only low concentrations of coconut oil and cocoa butter.

“The finding is remarkable because it means that a Crohn’s patient could also have a beneficial effect on their gut bacteria and inflammation by only switching the type of fat in their diet,” Alexander Rodriguez-Palacios, DVM, DVSc, PhD, the first author on the study and assistant professor of Medicine at Case Western Reserve University, said in a statement. “Patients would only need to replace a ‘bad’ fat with a ‘good’ fat, and eat normal amounts.”

Since this study is one of the first to indicate an association between changes in gut bacteria and Crohn’s disease, more studies are necessary to fully understand the influence of a “good” fat diet on fighting Crohn’s disease. Even so, results from this study could assist doctors in treating their patients with Crohn’s disease and help them identify the bacteria to use in a probiotic.

“Not all ‘good’ fats might be good in all patients,” warned Rodriguez-Palacios. “Mice indicate that each person could respond differently. But diet is something we are very hopeful could help at least some patients without the side-effects and risks carried by drugs. The trick now is to really discover what makes a fat ‘good’ or ‘bad’ for Crohn’s disease.”

 
Copyright AJMC 2006-2018 Clinical Care Targeted Communications Group, LLC. All Rights Reserved.
x
Welcome the the new and improved AJMC.com, the premier managed market network. Tell us about yourself so that we can serve you better.
Sign Up
×

Sign In

Not a member? Sign up now!