Adolescents who have had family members deported or detained were linked with poor psychological outcomes; AstraZeneca's phase 3 CASPIAN trial failed to meet its primary endpoint; tips on how to destress when you feel overwhelmed.
A survey of 547 Latino adolescents published in JAMA Pediatrics found that family deportation and detainment was associated with poor psychological outcomes among participants in suburban Atlanta, Georgia. Reported in Medpage Today, researchers found that those whose family members had been deported or detained within the past 6 months were significantly more likely than others to report suicidal ideation (adjusted odds ratio [aOR], 2.37; 95% CI, 1.06-5.29), alcohol use (aOR, 2.98; 95% CI, 1.26-7.04), and externalizing behaviors such as truancy or aggression (aOR, 2.76; 95% CI, 1.11-6.84).
AstraZeneca announced today that their phase 3 CASPIAN trial examining the efficacy of a second immunotherapy, tremelimumab, added to durvalumab (Imfinzi) in combination with a choice of standard-of-care (SoC) chemotherapies failed to meet its primary endpoint of demonstrating a statistically significant improvement in overall survival (OS) compared with durvalumab and SoC for patients with extensive-stage small cell lung cancer (ES-SCLC) treated in the firstline setting. It did, however, exhibit a sustained, clinically meaningful OS benefit for patients with ES-SCLC. Imfinzi, meanwhile, was granted a prority review by the FDA and had its Prescription Drug User Fee Act date set for the first quarter of this year. In dealing with stress, an indicator of high blood pressure when chronic, Idaho Falls magazine provided 8 tips on how to destress when feeling overwhelmed. In the tips, authors highlight the need for breathing deeply and going for a walk, 2 steps that can help guide users to safely relieve built-in stress. Additionally, diet and sleep play key roles in promoting cognitive function, which the researchers indicate can assist users in tackling issues with greater fervor. The role of technology was noted as a potential stress-inducer as well, citing the need to turn off one’s cell phone to limit distractions.
Overcoming Employment Barriers for Lasting Social Impact: Freedom House 2.0 and Pathways to Work
April 16th 2024To help celebrate and recognize National Minority Health Month, we are bringing you a special month-long podcast series with our Strategic Alliance Partner, UPMC Health Plan. Welcome to our second episode, in which we learn all about Freedom House 2.0 and the Pathways to Work program.
Listen
Government agencies have created an online portal for the public to report potential anticompetitive practices in health care; there are changes coming to the “boxed warning” section for chimeric antigen receptor T-cell therapies (CAR T) to highlight T-cell blood cancer risk; questions about the safety of obesity medications during pregnancy have arisen in women on them who previously struggled with fertility issues.
Read More
Making Giant Strides in Maternity Health Through Baby Steps
April 9th 2024To help celebrate and recognize National Minority Health Month, we are kicking off a special month-long podcast series with our strategic alliance partner, UPMC Health Plan. Welcome to our first episode, which is all about the Baby Steps Maternity Program and its mission to support women throughout every step of their pregnancy journey.
Listen
Gene, Light Therapy Combo Shows Promise Against Prostate Cancer Cells in Proof-of-Concept Study
April 18th 2024In their preclinical model, the researchers found efficacy both in vitro and in vivo by using CRISPR-Cas9 to mimic porphyria and combining the technology with light therapy.
Read More