Providers

A discussion at the National Comprehensive Cancer Network 2021 Virtual Congress: Biomarkers in Solid Tumors addressed the advantages and considerations for broad and targeted genomic profiling in oncology.

Real-world patients with moderate-to-severe psoriasis were shown to exhibit impaired efficacy with guselkumab treatment if they had history of prior biologic use, particularly anti-interleukin (IL)-17 exposure, with heavier patients linked with delayed onset of therapeutic response.

Unlike other options in the past, teprotumumab actually addresses bulging eye and double vision associated with thyroid eye disease (TED), which patients primarily care about, explained Robert G. Fante, MD, FACS, president of the American Society of Ophthalmic Plastic & Reconstructive Surgery and facial plastic surgeon and cosmetic surgeon, Fante Eye & Face Centre in Denver, Colorado.

Whether or not a child’s vision is impacted by ptosis, there are usually alternatives to surgery, which is elective, said William Katowitz, MD, attending surgeon in the Division of Ophthalmology at Children's Hospital of Philadelphia.

Recent research from the United Kingdom sought to understand more about factors that may impact the location of death for patients with Parkinson disease (PD) and multiple sclerosis (MS).

Although the authors say their findings shed light on possible disruptions to insulin supply during COVID-19, they note they could not adjust for those with diabetes who died.

Michael E. Chernew, PhD, co-editor-in-chief of The American Journal of Managed Care®, discussed cost and sustainability issues specific to commercial insurance, Medicare, and Medicaid at the National Alliance 2021 Annual Forum held in a hybrid format in Washington, DC.

Adults with atopic dermatitis were shown to be at lower risk of developing asthma if they were vaccinated against influenza, particularly those who adhered to yearly shots.

Findings of a real-world, single-center study indicated that apremilast was effective and safe long-term in the treatment of moderate-to-severe plaque psoriasis.

The American Society of Ophthalmic Plastic & Reconstructive Surgery 2021 Fall Scientific Symposium will feature presentations on oculofacial surgery innovations, social justice and diversity, and more.

Findings of an abstract presented at CHEST 2021 indicated that antidepressant use was associated with increased REM sleep latency and a complete lack of REM sleep, which may contribute to the poorer quality-of-life scores observed in these patients.

At the American Society of Ophthalmic Plastic & Reconstructive Surgery (ASOPRS) 2021 Fall Scientific Symposium, Shoaib Ugradar, MD, UCLA Stein Eye Center Santa Monica, will receive an award for his work on floppy eyelid syndrome and using collagen cross-linking to stiffen the eyelid and help patients.

The United States lifts travel restrictions for numerous countries, requiring proof of vaccination and in some cases negative COVID-19 tests; discrimination of any kind was associated with greater risk of mental health problems in young people; a controversial Alzheimer disease drug faces several uptake issues.

Richard Wasserman, MD, PhD, an allergist and immunologist with Allergy Partners of North Texas, an early adopter of food allergy oral immunotherapy (OIT), discusses how attitudes have changed around the practice.

Posters presented at the Academy of Managed Care Pharmacy Nexus 2021 meeting analyzed patient and physician perspectives on blood transfusions in acute myeloid leukemia (AML).

With new and expected future options for treating atopic dermatitis (AD), including an injectable biologic and an oral small molecule inhibitor, which is preferred and which makes the most sense for patients?

In 2017, guidelines about when to feed peanuts to infants changed to recommend early feeding by 4 to 6 months of age depending on 3 risk levels, but these allergy prevention strategies are still not widespread, according to Ruchi Gupta, MD, MPH, professor of pediatrics and medicine, Northwestern Feinberg School of Medicine, who discussed the topic at the 2021 ACAAI Annual Scientific Meeting.

Robert J. Hopkin, MD, clinical geneticist, Cincinnati Children's Hospital Medical Center, speaks on the symptom burden and current therapeutic interventions available for Fabry disease.

Daniel Greer, PharmD, BCPP, clinical assistant professor, Rutgers Ernest Mario School of Pharmacy, speaks on at-risk populations of chronic insomnia, and the reciprocal relationship between the condition and other comorbidities.

Several biomarkers identified by comprehensive genomic profiling were found to predict efficacy and toxicity of chemo-radiotherapy in patients with non–small cell lung cancer (NSCLC), with progression-free survival and overall survival outcomes associated with some of the identified genes.

Children with severe atopic dermatitis were shown to be at nearly 2-fold greater risk of both depression and internalizing behaviors, with mild disease also associated with internalizing behaviors in those as young as 4 years of age.

A greater proportion of biologic-naive patients with psoriatic arthritis treated with ixekizumab vs adalimumab achieved the combined endpoint of 100% resolution in the Psoriasis Area Severity Index and 50% or greater improvement in the American College of Rheumatology criteria at week 24 and 52.

Patients with obstructive sleep apnea with adequate continuous positive airway pressure (CPAP) therapy adherence exhibited significant reductions in diastolic blood pressure long term, compared with counterparts with poor adherence.

Patients with inflammatory bowel disease (IBD) treated with adalimumab had greater risk of developing psoriasis than those administered infliximab, with gender and smoking incidence also linked with greater IBD risk.

Panelists from a session at Asembia 2021 Specialty Pharmacy Summit in Las Vegas discussed considerations for manufacturers, specialty pharmacies, and payers entering the rare disease and gene therapy market.