Clinical

The diabetes drug metformin is being used in some cancer treatment trials, but study results show the use of metformin does not improve survival of patients with pancreatic ductal adenocarcinoma.

The incidence rate for heart failure dropped steeply over a decade in a population-based study, and while hospitalization rates remained steady over time, causes shifted from cardiovascular to noncardiovascular.

New legislation introduced by a bipartisan group of US senators would make it more difficult for new and generic opioid drugs to obtain the approval of the FDA.

A qualitative study to understand clinical providers' attitudes and beliefs about polypharmacy and their perceived barriers to and facilitators of appropriate medication discontinuation.

The total number of breast cancer cases in the United States is forecast to be 50% greater in 2030 than it was in 2011 driven mostly by a marked increase in cases of estrogen receptor-positive tumors.

While statins can prevent disease in older adults, they can also cause potentially serious side effects that could outweigh the benefits, according to a study published in the Annals of Internal Medicine.