Cost Prevents Approval of Revlimid in the UK...Again

NICE rejected Celgene's Revlimid again for treating patients with myelodysplastic syndrome, quoting concerns with cost-effectiveness of the drug.

Patients with a specific type of bone marrow disorder in England and Wales will be disappointed by news that cost regulators have not approved National Health Service use of Celgene's Revlimid (lenalidomide).

In draft guidance published this week, the National Institute for Health and Care Excellence (NICE) has turned down funding for the drug in patients with myelodysplastic syndromes characterised by a a certain chromosomal abnormality called a deletion 5q cytogenetic abnormality.

This is because while clinical experts told the committee that Revlimid is an effective therapy, the data provided by Celgene "showed uncertainty about whether lenalidomide actually extended lives", the Institute said, although it's Committee did concede that a survival benefit was plausible.


Source: PharmaTimes online