Scientists have shown new genetic evidence that could strengthen the link between the role of dietary fats and colon cancer progression.
The study, led by Arizona State University researcher and physician Raymond DuBois, has identified a molecular culprit, called peroxisome proliferator-activated receptor delta (PPAR delta), which, when deleted in a mouse model of colon cancer, stopped key steps required for the initiation and progression of tumor growth.
"This study has shown without a doubt there is a new function for a key molecule, PPAR delta, in the initiation and progression of colon cancer," said DuBois, executive director of ASU's Biodesign Institute. "These results also provide a new rationale for developing therapeutics that could block PPAR delta to treat inflammatory bowel disease and colorectal cancer."
Read the complete press release here: http://bit.ly/1f26xVu
Source: Arizona State University News