An educational nursing program can positively impact medication compliance in patients receiving oral pulmonary arterial hypertension (PAH) therapies.
An educational nursing program can positively impact medication compliance in patients receiving oral pulmonary arterial hypertension (PAH) therapies, according to research presented at AMCP 2021, the annual meeting of the Academy of Managed Care Pharmacy, held virtually April 12-16.
PAH therapies do not reverse, halt, or cure the chronic disease. Instead, they improve pulmonary hemodynamics and offer symptom relief. However, because medication tolerance and compliance are a challenge, health care providers can play a role in improving adherence.
“In-home nurse visits offer disease state education, discuss therapy expectations, and provide support tools for patients when experiencing adverse events that might lead to therapy discontinuation,” the researchers explained.
They evaluated the impact of in-home or face-to-face education visits on oral PAH therapy compliance by comparing patients who were supported by a nursing program with patients who were not.
The researchers used CVS Health pharmacy claims to identify 2 groups: the study group was patients (n = 197) on riociguat, selexipag, or treprostinil who were supported by a nursing program and the control group was patients (n = 213) on bosentan, ambrisentan, or macitentan who were not supported by a nursing program. All therapies were oral PAH therapies and the study claims covered January 2018 to June 2019.
The study compared the following between the 2 groups:
The study accounted for demographic and medication factors associated with adherence using a generalized linear model and logistic regression.
After 6 months, the study found patients in the study group:
Patients in the control group were 1.5 times more likely to drop their therapy in the first 6 months.
According to the authors, the significant improvement in MPR and therapy persistence highlighted the success of the educational nursing program in improving overall medication compliance to oral PAH therapies.
“While our study compared two different PAH therapy classes, a multidisciplinary patient support approach contributed to improved patient outcomes,” the authors concluded.
References
Sourounis E, Kyrychenko P, Avalos-Reyes E, Bagford D, Grover R, Feczko L. Effects of face-to-face educational nursing support on patient compliance with oral PAH therapies. Presented at: AMCP 2021; April 12-16, 2021. Abstract I6.
Navigating Health Literacy, Social Determinants, and Discrimination in National Health Plans
February 13th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the February 2024 issue of The American Journal of Managed Care® about their findings on how health plans can screen for health literacy, social determinants of health, and perceived health care discrimination.
Listen
The Supreme Court seems likely to reject a challenge to the abortion pill mifepristone; the FDA is inspecting far fewer pharmaceutical companies conducting clinical research; AstraZeneca has sued to block an Arkansas law that it said would unlawfully expand the 340B program to include for profit-pharmacy chains.
Read More
Drs Raymond Thertulien, Joseph Mikhael on Racial Disparities in Multiple Myeloma Care Access
December 28th 2023In the wake of the 2023 American Society of Hematology Annual Meeting and Exposition, Raymond Thertulien, MD, PhD, of Novant Health, and Joseph Mikhael, MD, MEd, FRCPC, FACP, chief medical officer of the International Myeloma Foundation, discussed health equity research highlights from the meeting and drivers of racial disparities in multiple myeloma outcomes.
Listen