Opinion

Video

Examining FMT for Patients With Recurrent C Difficile infections

Key Takeaways

  • FMT restores gut microbiota balance by transferring stool from healthy donors, mainly for recurrent C. difficile infections.
  • Recent data shows FMT's high efficacy in preventing recurrent C. difficile, outperforming standard antibiotic treatments.
SHOW MORE

The panelist discusses how fecal microbiota transplantation (FMT) involves transferring stool from healthy donors to restore gut microbiota in patients with recurrent Clostridioides difficile infection, though safety concerns include potential pathogen transmission and careful donor screening requirements, while OpenBiome’s standardized frozen FMT preparations have helped advance accessibility but should be used according to current FDA guidance for investigational use.

Video content above is prompted by the following:

  • Describe how FMT works and for which patients this can be used.
  • What has recent data shown about the efficacy of FMT in preventing recurrent C difficile?
  • What are the safety concerns when using FMT?
  • Discuss the recent updates of an investigational FMT therapy from OpenBiome, and how this impacts your clinical decision-making.

Newsletter

Stay ahead of policy, cost, and value—subscribe to AJMC for expert insights at the intersection of clinical care and health economics.

Related Videos
Dr Carrie Kitko
Dr Ibrahim Aldoss
1 expert is featured in this series.
Miriam Freimer, MD
Related Content
AJMC Managed Markets Network Logo
CH LogoCenter for Biosimilars Logo