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Utilizing Antibiotics in Treatment of C Difficile

Key Takeaways

  • Antibiotics can disrupt gut microbiota, leading to potential recurrences of Clostridioides difficile infections (CDI).
  • New therapies like fecal microbiota transplantation (FMT) and monoclonal antibodies aim to restore healthy gut flora and provide targeted immune support.
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The panelist discusses how antibiotics are paradoxically both the primary treatment for Clostridioides difficile infections and a major risk factor for recurrence since they disrupt the protective gut microbiome, which led to the development of alternative therapies like fecal microbiota transplantation to restore microbial balance and prevent reinfection.

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