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Expanded DNA Testing Might Allow Personalized Breast Cancer Treatment
Testing the entire genetic makeup -- or all the DNA -- of tumor cells from women with advanced breast cancer may help identify patients who could be helped by specific treatments, according to new research.
Testing the entire genetic makeup -- or all the DNA -- of tumor cells from women with advanced breast cancer may help identify patients who could be helped by specific treatments, according to new research.
The approach is considered the wave of the future by both the French researchers who conducted the study and U.S. experts.
"It is possible to deliver personalized medicine," said study researcher Dr. Fabrice Andre, of the Gustave Roussy Institute in Villejuif, France. "Until now, we could [test] one gene in a large number of patients, or larger numbers of genes in a few patients."
In the new study, the researchers evaluated the whole genome -- the entire collection of a person's genes -- of more than 400 patients. The approach is much more extensive than testing for mutations in specific genes, such as the BRCA1 and BRCA2 genetic mutations known to raise the risk of breast cancer.
Read the full story here: http://bit.ly/1eFukI7
Source: Philly.com
Oncology Onward: A Conversation With Penn Medicine's Dr Justin Bekelman
December 19th 2023Justin Bekelman, MD, director of the Penn Center for Cancer Care Innovation, sat with our hosts Emeline Aviki, MD, MBA, and Stephen Schleicher, MD, MBA, for our final episode of 2023 to discuss the importance of collaboration between academic medicine and community oncology and testing innovative cancer care delivery in these settings.
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Trastuzumab Deruxtecan Receives FDA Approval for HER2-Positive Solid Tumors
April 5th 2024FDA granted accelerated approval to trastuzumab deruxtecan-nxki for adult patients with unresectable or metastatic HER2-positive solid tumors who received prior systemic treatment and have no satisfactory alternative treatment options.
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