- Center on Health Equity and Access
- Clinical
- Health Care Cost
- Health Care Delivery
- Insurance
- Policy
- Technology
- Value-Based Care
Segment 5 - Surrogate End Points in Clinical Trials: The Right Information?
For approval of therapies in oncology, clinical trials aim to demonstrate improved overall survival of a treatment compared with a comparator or control arm. However, looking for improvement in overall survival can take an extended period of time, and in some cases may be unethical due to study design. Therefore, with the hope of getting an effective drug approved and on the market sooner, researchers are using surrogate end points, including progression-free survival, time-to-treatment failure, and time to progression.
Richard W. Joseph, MD, describes how progression-free survival can be a useful end point and can also help to assess quality of life, an important measure for patients. Ira M. Klein, MD, MBA, FACP, brings up the question, “What are we paying for? Cure? Long-term remission? Quality of life?”
Watch our related Peer Exchange, Oncology Stakeholder Summit 2014: Evidence-Based Decisions to Improve Quality and Regulate Costs
Examining Low-Value Cancer Care Trends Amidst the COVID-19 Pandemic
April 25th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the April 2024 issue of The American Journal of Managed Care® about their findings on the rates of low-value cancer care services throughout the COVID-19 pandemic.
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Oncology Onward: A Conversation With Penn Medicine's Dr Justin Bekelman
December 19th 2023Justin Bekelman, MD, director of the Penn Center for Cancer Care Innovation, sat with our hosts Emeline Aviki, MD, MBA, and Stephen Schleicher, MD, MBA, for our final episode of 2023 to discuss the importance of collaboration between academic medicine and community oncology and testing innovative cancer care delivery in these settings.
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