Amitkumar Mehta, MD, MBA
Articles
Potential Impact of Emerging Therapies on Patients Living with ITP
An expert discusses the rapidly evolving landscape of ITP treatments, highlighting emerging therapies such as Bruton’s tyrosine kinase inhibitors, neonatal Fc receptor antagonists, anti-CD38 antibodies, and innovative approaches like CAR T-cell therapy that offer new hope for improved patient outcomes.
Navigating Refractory ITP: Clinical Insights and Treatment Strategies
An expert discusses the expanded treatment options for refractory ITP, emphasizing accurate diagnosis, combination therapies targeting platelet production and destruction, and the evolving role of splenectomy with improved safety measures.
Defining Treatment Success, Failure, and When to Reassess Patients’ Management of ITP
An expert discusses how ITP treatment success is monitored through maintaining safe platelet levels and symptom control, managing relapses, and tailoring follow-up based on therapy type and patient needs.
Risks versus Benefits: ITP Treatment Side Effects and the Influence on Patients’ Quality of Life
An expert discusses the importance of balancing efficacy with safety in ITP treatment, emphasizing cautious use of steroids, close monitoring of therapy-related side effects, and maintaining platelet counts just above bleeding thresholds to minimize long-term drug toxicity through personalized, informed care.
Addressing the Limitations of Current ITP Therapies
An expert discusses the importance of patient education and personalized, flexible treatment planning in managing chronic immune thrombocytopenic purpura (ITP), highlighting proactive strategies like emergency steroids, shared decision-making, and interdisciplinary care to align therapy choices with each patient’s lifestyle, preferences, and comorbidities.
Current Treatment Algorithm for Management of Immune Thrombocytopenia
An expert discusses treatment strategies for immune thrombocytopenic purpura (ITP), emphasizing individualized decisions based on platelet count, bleeding symptoms, and comorbidities, with options ranging from observation to urgent therapies like steroids or IVIG, and longer-term approaches tailored to patient health, treatment goals, and lifestyle considerations.
Clinical Decision-Making in ITP: Timing Treatment Initiation and Therapy Goals
An expert discusses treatment strategies for immune thrombocytopenic purpura (ITP), emphasizing individualized decisions based on platelet count, bleeding symptoms, and comorbidities, with options ranging from observation to urgent therapies like steroids or IVIG, and longer-term approaches tailored to patient health, treatment goals, and lifestyle considerations.
Key Clinical Signs and Symptoms Used in Diagnosis of Immune Thrombocytopenia
An expert discusses the clinical presentation and diagnosis of immune thrombocytopenic purpura (ITP), emphasizing that isolated thrombocytopenia with mucosal bleeding and petechiae is highly suggestive of ITP, while underscoring the importance of ruling out other causes—especially drug-induced thrombocytopenia—through careful evaluation.
