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The decision was supported by efficacy data from 36 patients from the ongoing phase 1/2 HGB-206 trial (NCT02140554) and 2 patients in the phase 3 HGB-210 trial (NCT04293185). It was the second approval from FDA for a gene therapy for sickle cell disease.

FDA Approves bluebird bio's Lovo-Cel Gene Therapy for Sickle Cell Disease

She has a BA in journalism & media studies and Spanish from Rutgers University. You can connect with Rose on 

Recent decades have seen marked improvements in hematological cancer outcomes and an expanded armamentarium of therapies, but novel treatments require updated strategies that are not always easy to fine-tune, according to presenters at the 2023 American Society of Hematology Annual Meeting and Exposition. 

Cellular Therapies in Lymphoma Bring Hope, But Optimizing Their Use Remains a Challenge

A phase 4 study found severe asthma can be controlled using biologic therapies, without the addition of high-dose inhaled steroids. 

Severe Asthma Can Be Controlled Without High-Dose Inhaled Steroids, Study Finds 

Mary Caffrey is the Executive Editor for The American Journal of Managed Care® (

®). She joined AJMC® in 2013 and is the primary staff editor for 

the multistakeholder publication that reaches 22,000+ oncology providers, policy makers and formulary decision makers. She is also part of the team that oversees speaker recruitment and panel preparations for 

®'s premier annual oncology meeting, Patient-Centered Oncology Care®. For more than a decade, Mary has covered ASCO, ASH, ACC and other leading scientific meetings for 

Mary has a BA in communications and philosophy from Loyola University New Orleans. You can connect with Mary on 

Extended follow-up data presented at the American Society of Hematology show the advantage seen a year ago has held up for the second-generation BTK inhibitor.

ALPINE: After 39 Months, Zanubrutinib Keeps Its PFS Edge Over Ibrutinib in R/R CLL; Especially for High-Risk Patients

The American Journal of Managed Care provides insights into the latest news and research in managed care across multimedia platforms.

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This article provides insight into health care purchaser priorities and considerations for direct contracting opportunities, along with considerations for interested accountable care organizations.

Direct Contracting With Accountable Care Organizations: The Purchaser Perspective

Brian Klepper, PhD

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