Trends in Opioid and Nonsteroidal Anti-Inflammatory Use and Adverse Events
March 15th 2018Opioid use incidence and prevalence rates decreased with implementation of an opioid safety initiative, whereas nonsteroidal anti-inflammatory drug rates remained constant. Rates of adverse events were higher among opioid users.
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Assessing the Chiral Switch: Approval and Use of Single-Enantiomer Drugs, 2001 to 2011
March 14th 2014From 2001 to 2011, the US Food and Drug Administration approved 9 single-enantiomer drugs with racemic precursors. None showed pre-approval evidence of improved efficacy over the racemic precursor.
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