Dr Helen Shih on Low-Grade Gliomas: Wait or Treat?
Helen Shih, MD, MS, MPH, FASTRO, Massachusetts General Hospital, weighs the risks and benefits of treating or postponing treatment of low-grade gliomas.
Dr Tina Cascone Details Impact of Nivolumab Chemo-Immunotherapy on NSCLC
Tina Cascone, MD, PhD, of the University of Texas MD Anderson Cancer Center, discusses the impact of the CheckMate 77T study on the treatment approach for non–small cell lung cancer (NSCLC).
Dr Thomas Powles Discusses Impact of EV+P Therapy on Urothelial Carcinoma Treatment
Thomas Powles, MD, MBBS, MRCP, from Barts Cancer Centre, shares insights from the EV-302/KEYNOTE-A39 trial and its implications for the future of enfortumab vedotin and pembrolizumab (EV+P) combination therapy for urothelial carcinoma.
Coverage in Health Equity: October 2023
Health equity coverage appearing in the October 2023 issue of Evidence-Based Oncology.
Dr Kevin Kalinsky Shares Real-World Data on Effects of Sacituzumab Govitecan-hziy in TNBC
Kevin Kalinsky, MD, MS, of Glenn Family Breast Center, gives insight into the real-world data supporting the use of sacituzumab govitecan-hziy in the treatment of triple-negative breast cancer (TNBC).
Dr Max Parmar Details the Usefulness of MAMS Trial Designs
Max Parmar, professor of medical statistics and epidemiology at University College London, unpacks what clinicians and patients can gain from the application of multiarm multistage (MAMS) trials.
Dr Pawel Sobczuk Previews Timely Themes of ESMO Congress 2023
Pawel Sobczuk, MD, PhD, of the Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Poland, previews the upcoming ESMO Congress 2023 in Madrid, Spain.
Diaphragm Ultrasound Imaging Showcases Promise for Respiratory Assessments in SMA
In this prospective study, respiratory monitoring of patients with spinal muscular atrophy (SMA) benefited from the use of diaphragm ultrasound imaging.
Sociodemographic Status Correlates With MS Severity, Study Finds
In an observational cohort study, factors such as education, income, and marital status correlated with MS severity outcomes.
COVID-19 Infection Associated With Risk of Autoimmune, Autoinflammatory Disorders
A retrospective, population-based study reveals a possible association between COVID-19 infection and autoimmune and autoinflammatory outcomes.
Analysis Identifies Potential Biomarkers for RA Outcomes Throughout Pregnancy
A co-expression network analysis pinpoints different gene expressions that can potentially predict rheumatoid arthritis (RA) outcomes during pregnancy.
Study Suggests Physical Activity Could Mediate Fatigue in Patients With MS
Through a multitude of assessment tools, findings suggest that lower amounts of physical activity directly correlate with higher rates of fatigue in patients with relapsing-remitting multiple sclerosis (MS).
Study Validates the Positive Effects of Nusinersen on Bone Health in Patients With SMA Types 2 and 3
In a multidisciplinary follow-up study, researchers analyzed bone health decline and the effects of nusinersen in patients with spinal muscular atrophy (SMA) types 2 and 3.
IFGBP-2 Levels Indicative of Renal Prognosis in Pediatric Lupus Nephritis, Study Finds
In a cross-sectional study, insulin growth factor binding protein 2 (IFGBP-2) showed promise as a prognosis biomarker for renal disease in pediatric lupus nephritis (LN).
Q&A: Novel Therapy Holds Promise for Hypertension Treatment in Patients With Pacemakers
Atrioventricular interval modulation (AVIM) therapy for hypertension may help address this common comorbidity among patients with pacemakers.
FDA Accepts Dupilumab for Priority Review in Children Under 12 With EoE
If approved, the treatment would be the first of its kind for young children enduring eosinophilic esophagitis (EoE).
Surgery, Radiation for PCa Show Equal Efficacy in Candidates for Renal Transplantation
A recent study suggests that patients with high-risk prostate cancer (PCa) in need of renal transplantation should receive cancer treatment before their transplants, as surgery and radiation treatment for localized PCa appear to be equally effective in this patient population.
Oral N-Acetylglucosamine Treatment Benefits Management of MS, Study Finds
Researchers conducted a cohort study that suggests oral N-acetylglucosamine treatment can hinder neurodegeneration and inflammation associated with multiple sclerosis (MS).
Researchers Discern Possible Method for More Effective Diagnosis of PPMS
In a retrospective, real-world cohort study, the factors complicating the diagnosis of primary progressive forms of multiple sclerosis (PPMS) were explored.
Racial Differences in Chemokine Expression May Contribute to Prostate Cancer Disparities
Researchers found that analyzing certain chemokine levels may help explain racial disparities in prostate cancer lethality, and that neutralizing such chemokines could potentially benefit prostate cancer treatment.
Study Finds Systemic Postoperative Inflammation Contributes to Worsened Patient Outcomes
Persistent disability and risks of death were associated with inflammatory levels in patients following major abdominal surgery.
Rheumatoid Arthritis Is a Risk Factor for Aortic Stenosis, Study Finds
Researchers add to evidence suggesting that inflammatory factors contribute to increased risk for valvular heart diseases, such as aortic stenosis, in patients with rheumatoid arthritis.
COVID-19 Pandemic Affected Consistency of Care for Patients With PAH, Study Finds
An observational study confirms that the COVID-19 pandemic significantly disrupted care for patients with pulmonary arterial hypertension (PAH).
Poor Nutritional Index Scoring Predicts Worse Outcomes for PAH, Study Finds
This retrospective study found associations between inferior nutritional index scores, malnutrition, and prognoses in patients with pulmonary arterial hypertension (PAH).
Study Finds No Link Between Vaccines and MS Flare-Ups
Researchers add to previous studies by refuting association between vaccines and MS flare-ups.
Infections, Rather Than Inflammation or Autoimmune Disease, Associated With Dementia Development
A nationwide study conducted in Denmark found an association between dementia incidence and previous exposure to infection, but the potential impacts of systemic inflammation or autoimmune diseases on dementia incidence were not as clear.
Expert Panel Addresses Prostate Cancer Misconceptions, Importance of Screening
Panelists from the American College of Surgeons (ACS) and the American Urological Association spread awareness about the realities of prostate cancer, the importance of screening, and ways for men to approach their health concerns and prevention.
Inflammation Linked With Depression, Reduced Weight Loss After Bariatric Surgery
In a longitudinal case study, researchers found that higher inflammation levels may predict poor outcomes following bariatric surgery.
Study Explores Mechanisms of Cognitive Impairment in PAH
A cross-sectional study suggests that mild cognitive impairment is associated with pulmonary arterial hypertension (PAH).
Genetic Alterations Discovered in Hispanic Men With Prostate Cancer
In an exploratory analysis, Hispanic men with primary and metastatic prostate cancer exhibited higher frequencies of certain altered genes compared to non-Hispanic men.
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