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Cost-Effectiveness of Combinatorial Pharmacogenomic Testing for Treatment-Resistant Major Depressive Disorder PatientsUsing a state-transition probability analysis, this study assessed the long-term outcomes and economic implications of combinatorial pharmacogenomic testing for managing patients with major depressive disorder who were nonresponsive to treatments.
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Exploring Indications for the Use of Direct Oral Anticoagulants and the Associated Risks of Major BleedingThis supplement to The American Journal of Managed Care® describes the burden of thrombosis in terms of strokes and venous thromboembolism and highlights indications for the use of direct oral anticoagulants (DOACs) for the treatment of these conditions. The burden of DOAC-associated bleeding and unmet needs regarding reversal agents are also discussed.
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Impact of After-Hours Telemedicine on Hospitalizations in a Skilled Nursing FacilityA case study highlighting clinical and financial outcomes of an after-hours on-demand telemedicine intervention in a skilled nursing facility.
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Improvement of Outpatient Quality Metrics in a Limited-Resource SettingThis study presents an example of a population health initiative in a limited-resource primary care setting that led to significant improvements in preventive care quality metrics in the context of major insurance payers.
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Process of Care Compliance Is Associated With Fewer Diabetes ComplicationsAdherence to process of care measures was associated with reduced risk of 2 diabetes complications or any of 4 complications in a national industrial cohort.
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Case Study: How Does an ACO Generate Savings Three Years in a Row?Increasing accountable care organization savings is dependent on maximizing quality scores and increasing the number of beneficiaries while maintaining a low per-capita spend through efficiencies of care.
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Approaches for Overcoming Barriers to Cross-Sector Data SharingThe authors identified challenges to cross-sector data sharing and the approaches used to overcome these challenges in the Mid-Ohio Farmacy, a partnership to address food insecurity.
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New Start Versus Continuing Users on Aripiprazole: Implications for PolicyNew starts on aripiprazole were less adherent than continuing users. Prescriptions for 90-day supplies should be reserved for patients who have established effectiveness and tolerance.
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Importance of Reasons for Stocking Adult VaccinesEconomic factors associated with the purchase and maintenance of vaccine inventory and inadequate reimbursement for vaccination services were the most important to pharmacy and doctors’ office decision makers when considering whether to stock adult vaccines.
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Deprescribing in the Context of Multiple Providers: Understanding Patient PreferencesDeprescribing could reduce the risk of harm from inappropriate medications. Understanding patient attitudes regarding which clinicians can make deprescribing recommendations can facilitate effective design and implementation of interventions.
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Pricing of Monoclonal Antibody Therapies: Higher If Used for Cancer?The annual price of monoclonal antibody therapies used in oncology and hematology is about $100,000 higher than those used in other disease states.
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Beyond Regulatory Requirements: Designing ACO Websites to Enhance Stakeholder EngagementThe authors describe best practices for Web design in the accountable care organization space in order to enhance engagement with patients and providers.
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Veterans Health Administration Benefit Value Has Little Effect on RelianceRelying on veteran survey responses and novel actuarial data, the authors examine the relationship between benefit value and reliance on the Veterans Health Administration.
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Medical Homes and Cost and Utilization Among High-Risk PatientsA longitudinal case-control design was used to evaluate the effects of the patient-centered medical home model on medical costs and utilization among high-risk patients.
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Medicare Prescription Drug Plans as Perceived by Public Health ProvidersEven experienced providers say prescribing has become too complex and time consuming with Medicare Part D plans, which differ in formularies and prior authorization processes.
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Predictive Factors of Discharge Navigation Lag TimeExamination of factors associated with discharge lag time and how this metric plays an important role in managing hospital throughput.
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Impact of Clinical Training on Recruiting Graduating Health ProfessionalsA business case is made for medical centers to offer high-quality clinical training experiences to recruit graduating health professionals.
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Social Determinants of Health and Emergency Department Utilization in Alabama Children’s Health Insurance ProgramCommunity social determinants of health such as rurality and low socioeconomic status moderate the association between an individual’s race and emergency care use.
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Collaborative Care Before Accountable Care: Achieving Low-Cost, High-Quality Care Through a Regional Collaborative in FloridaAs accountable care organizations proliferate across the nation, delivery systems still struggle to balance quality improvement, cost containment, and migration toward accountable care. This paper describes the phased approach where the University of Florida Health Science Center and Shands Teaching Hospital and Clinics, Inc, and Orlando Health have jointly developed a series of clinical and health services that are of the highest quality and are offered at the lowest cost. The result is a regional collaborative that will be the foundation for a regional accountable care organization, first leveraging clinical core competencies, then moving to a more integrated model.
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Implementing an Oncology Precision Medicine Clinic in a Large Community Health SystemPrecision medicine is increasingly being utilized in oncology. Aurora Health Care has implemented Syapse software to integrate molecular data into the electronic health record to accommodate precision medicine findings.
