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Olaparib/Cediranib Misses Survival End Points in Relapsed Ovarian Cancer TrialTreatment with maintenance olaparib/cediranib demonstrated similar survival vs olaparib alone in platinum-sensitive relapsed ovarian cancer.
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Predictive Models for Low Birth Weight: A Comparative Analysis of Algorithmic Fairness–Improving ApproachesThis study compared 6 algorithmic fairness–improving approaches for low-birth-weight predictive models and found that they improved accuracy but decreased sensitivity for Black populations.
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Impact of Functional Recovery on Patients Having Heart SurgeryThis article describes the positive impact that actively managing functional recovery has on postacute placement for patients undergoing coronary artery bypass surgery.
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Reducing Delays in Breast Cancer Care Using an Innovative Digital Health PlatformThe use of a novel digital health platform achieved a 55% reduction in time to treatment among women with a new diagnosis of breast cancer.
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Contributor: Climate Change to Take an Increasing Toll on Mental HealthTo mark the nation's 52nd Earth Day, Robert Feder, MD, outlines how climate change will exacerbate mental health challenges and the importance of global efforts to address the crisis.
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The Feasibility and Equity of Text Messaging to Determine Patient Eligibility for Lung Cancer ScreeningText messaging shows promise for assessing smoking status and identifying lung cancer screening eligibility, particularly among middle-aged, educated individuals with medium or high income. However, a multimodal approach is crucial for equitable implementation of such a program.
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Hospital Performance in a Statewide Commercial Insurer Episode-Based Incentive ProgramSome hospitals were able to outperform others in a commercial insurer episode-based incentive program, but there was little evidence of global reductions in episode spending.
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Food Insecurity, Neighborhood, and Health Care Utilization in Health System AdultsThis retrospective study examined food insecurity and neighborhood disadvantage in health system patients as predictors of acute health care utilization.
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Classifying Clinical Work Settings Using EHR Audit Logs: A Machine Learning ApproachAn automated pipeline of frequency representation and machine learning models on raw electronic health record (EHR) audit logs can classify work settings based on clinical work activities.
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Type 2 Diabetes Patient Activation and mHealth Interventions Decreased Cardiovascular Disease RiskMobile health (mHealth) and a patient activation program could serve as a model for improving health outcomes for patients in outpatient clinical settings by decreasing atherosclerotic cardiovascular disease risk score.
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A Case Report of the Analytic Development of Bundled Payments for the Commercial MarketThis case report of a novel methodology for the analytic development of bundled payments addresses statistical analysis, data visualization, and clinical consultation.
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Modeling Financial Outcomes and Quantifying Risk in Episode-Based Payment ModelsThis article provides a description of prospective financial simulation methodology and use cases with empirical data for episode-based bundled payments, including implications for contract negotiations and value-based care redesign.
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Consumer Data Transparency Is More Important Than Ever as the Battle Against COVID Rages OnOn January 1, CMS implemented the Hospital Price Transparency final rule, but by July, it was clear that many hospitals were noncompliant. Even with a proposed rule for penalties, requirements still only fall on certain parts of the health care industry.
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First-Line Rucaparib Maintenance Reduces Progression Risk Across Prognostic Subgroups in HRD– High-Grade Ovarian CancerRucaparib maintenance improved progression-free survival (PFS) in homologous recombination deficiency (HRD)-negative advanced ovarian cancer, irrespective of baseline prognostic factors.
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Cost Savings Associated With Electronic Specialty ConsultationsThis retrospective cohort evaluation found that patients receiving electronic, compared with face-to-face, specialty consultation had significantly lower health care costs for at least 3 months.
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Hospital at Home: Paying for What It’s WorthA framework centered around cost, quality, and equity is essential to define the value of hospital-at-home programs.
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Varied Use of Step Therapy Among Medicare Advantage PlansThe frequency with which 7 of the largest Medicare Advantage plans impose step therapy protocols in their Part B drug coverage decisions varies substantially.
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Chemotherapy-Induced Peripheral Neuropathy in Metastatic Breast Cancer Patients Initiating Intravenous Paclitaxel/nab-PaclitaxelWe examine the incidence and impact of chemotherapy induced peripheral neuropathy on clinical and economic outcomes in women with metastatic breast cancer initiating intravenous paclitaxel/nab-paclitaxel.
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Sacubitril/Valsartan in Medicare Alternative Payment ModelsOptimizing utilization of sacubitril/valsartan for treatment of heart failure could improve provider performance in the Bundled Payments for Care Improvement initiative and the Medicare Shared Savings Program.
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Variation in Fracture Risk Estimation Among East Asian WomenFracture prediction tools for East Asian individuals vary by country. In the United States, the US-Asian Fracture Risk Assessment Tool provides hip fracture probabilities that correspond to observed estimates.
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How Do Primary Community Hospitals Enact Early Response to COVID-19? The Experience From Chengdu, ChinaOur hospital is a primary hospital in Chengdu, China. Since February 5, our hospital has been listed as the primary designated medical unit for treating new patients with coronavirus disease 2019 (COVID-19) in Jinniu District. In this letter, we share our COVID-19 experience with readers.
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Implementation and Cost Validation of a Real-time Benefit ToolThis study evaluates impact of a real-time benefit tool on medication access and physician and pharmacy workflows at a large academic medical center.
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Financial Factors That Influenced Telemedicine Delivery During the COVID-19 PandemicThis study describes financial issues that influenced telemedicine provision and use for patients with chronic conditions and their providers during COVID-19.
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Experts Share Top Takeaways From AACR Annual Meeting 2025During interviews at the American Association for Cancer Research (AACR) Annual Meeting 2025, experts shared key insights from this year's conference.
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Predicting Hospital Readmission in Medicaid Patients With Diabetes Using Administrative and Claims DataA statistical model based entirely on claims data can accurately predict 30-day hospital readmission in Medicaid patients with diabetes.
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Sacubitril/Valsartan in Medicare Alternative Payment ModelsOptimizing utilization of sacubitril/valsartan for treatment of heart failure could improve provider performance in the Bundled Payments for Care Improvement initiative and the Medicare Shared Savings Program.
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Relationships Between Patient Portal Activation and Patient Satisfaction Scores Among CG-CAHPS and HCAHPS RespondentsPatients with activated patient portal accounts report higher patient satisfaction in respective dimensions of the Clinician and Group Consumer Assessment of Healthcare Providers and Systems (CG-CAHPS) and Hospital CAHPS (HCAHPS) surveys compared with patients without portal accounts.
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Care Transitions for Young Adults With Special Health Care NeedsA Medicaid managed care plan developed a pilot program to assist special needs youth with transition to adult care. Case studies and discussion present findings.
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Provider Perceptions of Pharmacists in Primary Care–Based Accountable Care OrganizationsIn this article, the authors describe their experiences addressing provider perceptions and methods to overcome several challenges to clinical pharmacist integration in primary care–based accountable care organizations.
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Implementing Team-Based Telemedicine Workflows in Safety-Net Primary CareTelemedicine in safety-net primary care faces particular challenges. Consistent, team-based workflows can support video visit implementation and health care maintenance in telemedicine visits.
