Research Identifies How Tumor Cells Migrate to Bones
June 22nd 2019Bone is one of the most frequent sites of metastasis in breast cancer, but the exact reasons for this high risk of bone metastases has not been well understood. However, research has found that physics may be partly the reason for this high risk.
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Despite Mortality Risk, Women Over 80 With Osteoporosis Have High 5-Year Risk of Hip Fracture
June 19th 2019Women 80 years or older with osteoporosis have a high hip fracture probability even when accounting for mortality risk, suggesting that these patients are candidates for drug treatment to prevent hip fractures.
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Evaluating Use of Bone-Modifying Agents to Treat Skeletal-Related Events in Cancer
June 15th 2019Skeletal-related events are frequent complications in patients with cancers. Two abstracts analyzed the use of bone-modifying agents in patients with newly diagnosed multiple myeloma and breast cancer.
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How Cells Slow Cancer That Has Reached Bone
May 23rd 2019New research has identified how bone cells subdue cancer cells that have reached the bone so that the cancer cells remain dormant for decades. The finding may help researchers develop new treatments to prevent or treat metastatic disease and put cancer cells to sleep permanently.
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Providing Pain Relief for Patients With Bone Metastases
May 18th 2019Multifraction radiotherapy is standard to treat pain in patients with bone metastases that are mostly not in their spine, but new research has shown that single-fraction stereotactic body radiotherapy had higher rates of overall pain response and better local disease control.
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Bisphosphonates Are Increasingly Prescribed to Those Most Likely to Benefit
May 8th 2019Bisphosphonates, which are used to treat osteoporosis and prevent fractures, are increasingly being used more effectively in a population more likely to benefit, according to results presented at ENDO 2019, the Endocrine Society’s annual meeting.
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Treatment Could Prevent Patients With Cancer From Experiencing Jawbone Damage After Oral Surgery
May 4th 2019Patients with cancer who receive high doses of bisphosphonates, used to treat bone cancer, can experience jaw damage. New preclinical research published in Bone Science Direct could prevent these patients from experiencing this loss of jawbone tissue after routine oral surgery.
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Ultrasound Is Cost-Effective Way to Increase Bone Health Screenings, Study Finds
April 27th 2019Ultrasound can be a cost-effective alternative to dual-energy x-ray absorptiometry, which is considered the gold standard for assessing bone health but has limited use due to the the cost, size, and technical needs required to operate the machine.
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Denosumab Improves Bone Health, Disease-Free Survival in Hormone Receptor–Positive Breast Cancer
April 23rd 2019The addition of denosumab to aromatase therapy results in a significant reduction in clinical fractures and yields benefits for disease-free survival in postmenopausal women with hormone receptor–positive, early-stage breast cancer.
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Dim Light at Night May Help Spread Breast Cancer to Bones
April 18th 2019When breast cancer spreads, it often goes to the bones, and new research has found that exposure to dim light at night may contribute to this spread. Results from the animal study were presented at ENDO 2019, the annual meeting of the Endocrine Society.
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