Immunology

Despite its impact on patient quality of life, hidradenitis suppurativa (HS) remains underdiagnosed and undertreated; authors outline what's being discovered within the treatment landscape.

A recent study identified a significant association between psoriasis and inflammatory bowel disease. This link also applied to IBD subtypes: Crohn disease and ulcerative colitis.

Approved in Europe, tabelecleucel may soon be considered by FDA to treat patients who develop Epstein-Barr virus following a transplant, which then triggers a type of deadly lymphoma that may not respond to traditional therapy. Tab-cel, an allogeneic T-cell therapy, comes 30 years after the discovery that T cells might offer hope, followed by decades of research on how to harness them without the side effects.

Findings reveal an increased risk of psoriatic arthritis (PsA) among female patients with severe skin psoriasis who have nail involvement and require oral systemic therapy for their condition.

A cross-sectional study finds that patients with rheumatoid arthritis receiving disease-modifying antirheumatic drugs (DMARDs) exhibit a reduced immune response to the COVID-19 vaccine compared with controls.

This new late-breaking data presented at ACR 2023 was the first clinical evidence indicating efficacy of afimetoran for those with cutaneous lupus erythematosus (CLE).

This new program was designed to be a scalable model for the formulation of similar initiatives in communities known to have limited access to specialized care for rheumatic conditions.

New data presented at ACR 2023 highlighted the differences in rates of flares and Boolean 2.0 remission rates compared to patients with rheumatoid arthritis who continued a tumor necrosis factor inhibitor (TNFi).

A nationwide cohort study linked biologic disease-modifying antirheumatic drugs with decreased risks for the onset of autoimmune thyroid disease in patients with rheumatoid arthritis.

In a cross-sectional study, insulin growth factor binding protein 2 (IFGBP-2) showed promise as a prognosis biomarker for renal disease in pediatric lupus nephritis (LN).

Patients with SLE who reported being more satisfied in their lives were more likely to have higher physical and mental component summary scores.

Vitamin D deficiency is associated with high inflammation and bone mineral density (BMD) decline in patients with systemic lupus erythematosus (SLE).

Adults at or under the age of 65 years who are frail and have systemic lupus erythematosus (SLE) increased the likelihood of repeated emergency department visits.

A study suggests that strains of ruminococcus (blautia) gnavus (RG) seen in the gut microbiome of patients in active lupus nephritis might be drivers of disease flares and highlight the possible pathogenic qualities of specific strains.